BDB563489
mTOR (pS2448) Mouse, PE, Clone: O21-404, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB563489-Each-of-1 | In Stock | ₹ 27,165.30 |
BDB563489 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 27,165.30
GST (18%): ₹ 4,889.754
Total Price: ₹ 32,055.054
Antigen
mTOR (pS2448)
Classification
Monoclonal
Conjugate
PE
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Phosphorylated Peptide
Quantity
50 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
O21-404
Description
Mammalian target of rapamycin; FRAP1; RAFT1; RAPT1
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human, Mouse, Rat
Isotype
IgG1 κ
Related Products
Description
- Description The O21-404 monoclonal antibody recognizes the human mammalian target of rapmycin,(mTOR) that is phosphorylated at serine residue 2448, mTOR (pS2448)
- mTOR belongs to the phosphoinositide-3-kinase (PI3K)-related (PIKK) family of kinases
- mTOR is also known as mechanistic target of rapamycin (serine/threonine kinase), FRAP, RAFT1, and RAPT1
- mTOR functions as an amino acid and ATP sensor to balance nutrient availability and cell growth
- When nutrients are sufficiently available, mTOR is activated by phosphorylation at serine residue 2448 through the PI3 kinase/Akt signaling pathway
- Phosphorylated mTOR in turn activates the p70 S6 kinase and contributes to the inactivation 4E-BP1, an elF4E inhibitor
- In this way, mTOR participates in the upregulation of cellular protein synthesis, growth, proliferation and survival
- mTOR function may be abnormally regulated in tumors.
Compare Similar Items
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Antigen: mTOR (pS2448)
Classification: Monoclonal
Conjugate: PE
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Phosphorylated Peptide
Quantity: 50 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: O21-404
Description: Mammalian target of rapamycin; FRAP1; RAFT1; RAPT1
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human, Mouse, Rat
Isotype: IgG1 κ
Antigen:
mTOR (pS2448)
Classification:
Monoclonal
Conjugate:
PE
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Phosphorylated Peptide
Quantity:
50 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
O21-404
Description:
Mammalian target of rapamycin; FRAP1; RAFT1; RAPT1
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human, Mouse, Rat
Isotype:
IgG1 κ
Antigen: PLZF
Classification: Monoclonal
Conjugate: Alexa Fluor 647
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Mouse PLZF Recombinant Protein
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: R17-809
Description: Zbtb16; zinc finger and BTB domain containing 16; zinc finger protein 145
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human, Mouse
Isotype: IgG1 κ
Antigen:
PLZF
Classification:
Monoclonal
Conjugate:
Alexa Fluor 647
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Mouse PLZF Recombinant Protein
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
R17-809
Description:
Zbtb16; zinc finger and BTB domain containing 16; zinc finger protein 145
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human, Mouse
Isotype:
IgG1 κ
Antigen: CD135
Classification: Monoclonal
Conjugate: Alexa Fluor 647
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Human FLT3 Transfected Cell Line
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 4G8
Description: FLK2; FLT-3; Fms-related tyrosine kinase 3; STK-1
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD135
Classification:
Monoclonal
Conjugate:
Alexa Fluor 647
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Human FLT3 Transfected Cell Line
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
4G8
Description:
FLK2; FLT-3; Fms-related tyrosine kinase 3; STK-1
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: IFN-gamma
Classification: Monoclonal
Conjugate: Alexa Fluor 647
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Partially purified human IFN-gamma from supernatants of human PBMC stimulated with Staphylococcus aureus
Quantity: 50 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 4S.B3
Description: IFNG; Interferon-gamma; IFG; IFI; Type II interferon
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Baboon, Cynomolgus, Human, Rhesus Monkey
Isotype: IgG1 κ
Antigen:
IFN-gamma
Classification:
Monoclonal
Conjugate:
Alexa Fluor 647
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Partially purified human IFN-gamma from supernatants of human PBMC stimulated with Staphylococcus aureus
Quantity:
50 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
4S.B3
Description:
IFNG; Interferon-gamma; IFG; IFI; Type II interferon
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Baboon, Cynomolgus, Human, Rhesus Monkey
Isotype:
IgG1 κ