BDB563690

CD16 Mouse anti-Human, Brilliant Violet 786, Clone: 3G8, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB563690-Each-of-1 In Stock ₹ 38,502.00

BDB563690 - Each of 1

₹ 38,502.00

In Stock

Quantity

1

Base Price: ₹ 38,502.00

GST (18%): ₹ 6,930.36

Total Price: ₹ 45,432.36

Antigen

CD16

Classification

Monoclonal

Conjugate

Brilliant Violet 786

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Baboon, Cynomolgus, Human, Rhesus Monkey

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

3G8

Description

FcRIII; Fc-gamma RIII; FCG3; FCGR3; FCGRIII; FcγRIII; IGFR3

Immunogen

Human polymorphonuclear leukocytes

Quantity

100 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Description

  • The 3G8 monoclonal antibody specifically binds to the 50-65 kDa transmembrane form of the IgG Fc Receptor (Fc γRIII), a human NK cell-associated antigen
  • CD16 is expressed on NK cells as well as macrophages and granulocytes
  • Reports indicate that CD16 plays a role in signal transduction and NK cell activation
  • The 3G8 antibody blocks the binding of soluble immune complexes to granulocytes
  • The 3G8 antibody is reported (Vossebeld et al ., 1997) to increase intracellular calcium levels in human neutrophils by interacting with both Fc γRIIa and Fc γRIIIb molecules
  • This antibody has also been reported to induce homotypic neutrophil aggregation
  • The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon™ Brilliant Violet™ family of dyes
  • This dye is a tandem fluorochrome of BD Horizon™ BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 786-nm
  • BD Horizon™ BV786 can be excited by the violet laser and detected in a filter used to detect Cy7™-like dyes (eg, 780/60-nm filter).

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Fischer Scientific

BDB563690

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Antigen:
CD16

Classification:
Monoclonal

Conjugate:
Brilliant Violet 786

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Baboon, Cynomolgus, Human, Rhesus Monkey

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
3G8

Description:
FcRIII; Fc-gamma RIII; FCG3; FCGR3; FCGRIII; FcγRIII; IGFR3

Immunogen:
Human polymorphonuclear leukocytes

Quantity:
100 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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BDB563694

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Antigen:
CD314

Classification:
Monoclonal

Conjugate:
Brilliant Violet 711

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG1

Applications:
Flow Cytometry

Clone:
CX5

Description:
Klrk1; NKG2D; NKG2-D; NK cell receptor D; Natural killer cell group 2D

Immunogen:
Purified Mouse NKG2D protein

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
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Classification:
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Conjugate:
Brilliant Violet 711

Host Species:
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Purification Method:
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RUO

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Human

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G46-6

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Primary or Secondary:
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Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
CD163

Classification:
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Conjugate:
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Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
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Target Species:
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Isotype:
IgG1 κ

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Primary or Secondary:
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Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.