BDB564182
CD85k Mouse anti-Human, Alexa Fluor 647, Clone: ZM3.8, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB564182-Each-of-1 | In Stock | ₹ 27,678.66 |
BDB564182 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 27,678.66
GST (18%): ₹ 4,982.159
Total Price: ₹ 32,660.819
Antigen
CD85k
Classification
Monoclonal
Conjugate
Alexa Fluor 647
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1
Applications
Flow Cytometry
Clone
ZM3.8
Description
LILRB4; ILT-3; HM18; LIRB4; LILRB5; LIR-5
Immunogen
Human ILT3 Recombinant Protein
Quantity
100 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- The ZM3.8 monoclonal antibody specifically binds to CD85k which is also known as Immunoglobulin-like transcript 3 (ILT-3) and Monocyte inhibitory receptor HM18
- CD85k is encoded by LILRB4 (Leukocyte immunoglobulin-like receptor, subfamily B member 4) and is expressed as a type I transmembrane glycoprotein
- CD85k is comprised of two C2-type Ig domains, a transmembrane region, and a cytoplasmic tail with three immunoreceptor tyrosine-based inhibitory motifs (ITIMs)
- CD85k is selectively expressed by myeloid antigen presenting cells including monocytes, macrophages, and dendritic cells
- CD85k functions as an inhibitory receptor
- ILT3 can also function in antigen capture and presentation
- It is efficiently internalized upon cross-linking, and delivers its ligand to an intracellular compartment where it is processed and ultimately presented by APCs to T cells
- Thus, ILT3 is a novel inhibitory receptor that can negatively regulate activation of APCs and can be used by APCs for antigen uptake
- ILT3 expression is upregulated on tolerogenic dendritic cells that can induce regulatory T cells.
Compare Similar Items
Show Difference
Antigen: CD85k
Classification: Monoclonal
Conjugate: Alexa Fluor 647
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1
Applications: Flow Cytometry
Clone: ZM3.8
Description: LILRB4; ILT-3; HM18; LIRB4; LILRB5; LIR-5
Immunogen: Human ILT3 Recombinant Protein
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD85k
Classification:
Monoclonal
Conjugate:
Alexa Fluor 647
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1
Applications:
Flow Cytometry
Clone:
ZM3.8
Description:
LILRB4; ILT-3; HM18; LIRB4; LILRB5; LIR-5
Immunogen:
Human ILT3 Recombinant Protein
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: VHL
Classification: Monoclonal
Conjugate: Alexa Fluor 647
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2b κ
Applications: Flow Cytometry
Clone: S2-647
Description: VHL1; pVHL; Elongin binding protein; Protein G7; HRCA1; RCA1
Immunogen: Human VHL Recombinant Protein
Quantity: 50 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
VHL
Classification:
Monoclonal
Conjugate:
Alexa Fluor 647
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ
Applications:
Flow Cytometry
Clone:
S2-647
Description:
VHL1; pVHL; Elongin binding protein; Protein G7; HRCA1; RCA1
Immunogen:
Human VHL Recombinant Protein
Quantity:
50 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD131
Classification: Monoclonal
Conjugate: Alexa Fluor 647
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: 3D7
Description: Cytokine receptor common β chain; CDw131; IL-3Rβ; IL-5Rβ
Immunogen: Human CD131 Transfected COS Cells
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD131
Classification:
Monoclonal
Conjugate:
Alexa Fluor 647
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
3D7
Description:
Cytokine receptor common β chain; CDw131; IL-3Rβ; IL-5Rβ
Immunogen:
Human CD131 Transfected COS Cells
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD123
Classification: Monoclonal
Conjugate: Brilliant Violet 786
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2a κ
Applications: Flow Cytometry
Clone: 7G3
Description: IL3RA; IL-3RA; IL-3Rα; IL-3R-alpha; Interleukin-3 receptor subunit alpha
Immunogen: Human IL-3Ra-transfected cells
Quantity: 50 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD123
Classification:
Monoclonal
Conjugate:
Brilliant Violet 786
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ
Applications:
Flow Cytometry
Clone:
7G3
Description:
IL3RA; IL-3RA; IL-3Rα; IL-3R-alpha; Interleukin-3 receptor subunit alpha
Immunogen:
Human IL-3Ra-transfected cells
Quantity:
50 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.