BDB564184

VHL Mouse anti-Human, Alexa Fluor 647, Clone: S2-647, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB564184-Each-of-1 In Stock ₹ 24,427.38

BDB564184 - Each of 1

₹ 24,427.38

In Stock

Quantity

1

Base Price: ₹ 24,427.38

GST (18%): ₹ 4,396.928

Total Price: ₹ 28,824.308

Antigen

VHL

Classification

Monoclonal

Conjugate

Alexa Fluor 647

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG2b κ

Applications

Flow Cytometry

Clone

S2-647

Description

VHL1; pVHL; Elongin binding protein; Protein G7; HRCA1; RCA1

Immunogen

Human VHL Recombinant Protein

Quantity

50 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The S2-647 monoclonal antibody recognizes the Von Hippel-Lindau (VHL) protein
  • The VHL protein is expressed within the cytosol and nuclei of cells from a variety of tissues
  • It serves as a tumor suppressor and transcriptional repressor that is highly conserved from Drosophila to mammalian species
  • VHL binds to Elongin B and C subunits and other proteins as part of a E3 ubiquitin ligase complex that targets a variety of proteins, including HIF-1 alpha and Beta-2 adrenergic receptors, for proteasomal degradation
  • Aberrant VHL expression is associated with a number of diseases including Von Hippel-Lindau disease, a familial cancer syndrome, that predisposes individuals to hemangioblastomas of the central nervous system and retina, pheochromocytoma and renal cell carcinoma
  • Three distinct VHL isoforms ranging in molecular weight from approximately 19-30 kDa have been described.

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BDB564184

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Antigen:
VHL

Classification:
Monoclonal

Conjugate:
Alexa Fluor 647

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
S2-647

Description:
VHL1; pVHL; Elongin binding protein; Protein G7; HRCA1; RCA1

Immunogen:
Human VHL Recombinant Protein

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
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Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
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Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
3D7

Description:
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Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Target Species:
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IgG2a κ

Applications:
Flow Cytometry

Clone:
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Description:
IL3RA; IL-3RA; IL-3Rα; IL-3R-alpha; Interleukin-3 receptor subunit alpha

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Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.