BDB564215

TLR4 (CD284) Mouse anti-Human, PE, Clone: TF901, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB564215-Each-of-1 In Stock ₹ 23,914.02

BDB564215 - Each of 1

₹ 23,914.02

In Stock

Quantity

1

Base Price: ₹ 23,914.02

GST (18%): ₹ 4,304.524

Total Price: ₹ 28,218.544

Antigen

TLR4 (CD284)

Classification

Monoclonal

Conjugate

PE

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

TF901

Description

TLR4; CD284; Toll-like Receptor 4; ARMD10

Immunogen

Human TLR4 Transfected Cell Line

Quantity

100 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The TF901 monoclonal antibody specifically binds to TLR4 (Toll-like receptor 4) which is also known as CD284
  • TLR4 is a 110 kDa type I transmembrane glycoprotein that belongs to the Toll-like receptor (TLR) family
  • TLR4 is expressed on monocytes, macrophages, granulocytes, dendritic cells and endothelial cells
  • TLR4 binds lipopolysaccharide (LPS) which is a major membrane component of Gram-negative bacteria
  • It thus acts as an innate immune recognition receptor against many pathogens
  • In association with MD-2, LPS binds to and signals through TLR4 receptors by MyD88-dependent and MyD88-independent pathways to induce the cellular production of proinflammatory cytokines
  • TF901 antibody binding is not influenced by the human TLR4 D299G/T399I polymorphism
  • Preincubation of TLR4-positive cells with the TF901 antibody blocks the subsequent binding of the HTA125 antibody which is also specific for human TLR4.

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Show Difference

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BDB564215

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Antigen:
TLR4 (CD284)

Classification:
Monoclonal

Conjugate:
PE

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
TF901

Description:
TLR4; CD284; Toll-like Receptor 4; ARMD10

Immunogen:
Human TLR4 Transfected Cell Line

Quantity:
100 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
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Conjugate:
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Purification Method:
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Applications:
Flow Cytometry

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Immunogen:
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Antigen:
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Classification:
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Conjugate:
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Host Species:
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Purification Method:
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Isotype:
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Primary or Secondary:
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