BDB564342
EMR2 (CD312) Mouse anti-Human, Alexa Fluor 647, Clone: 494025, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB564342-Each-of-1 | In Stock | ₹ 24,299.04 |
BDB564342 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 24,299.04
GST (18%): ₹ 4,373.827
Total Price: ₹ 28,672.867
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Description
- The 494025 monoclonal antibody specifically binds to EMR2 (Epidermal Growth Factor Module-containing Mucin-like Receptor 2) glycoprotein which is also known as CD312
- EMR2 belongs to the Epidermal Growth Factor-seven Span Transmembrane (EFG-TM7) family
- EMR2 is expressed by activated lymphocytes and myeloid cells
- CD312 can bind to the glycosaminoglycans, dermatan sulfate and chondroitin sulfate
- Upon cellular activation, CD312 expression increases and localizes to the leading edge of neutrophils and regulates their adhesion, migration and production of superoxide anion
- CD312 expression increases as monocytes differentiate into macrophages but decreases upon differentiation into dendritic cells
- EMR2 may also mediate some interactions between activated B cells that express chondroitin sulfate and activated dendritic cells, macrophages and T cells.