BDB561815

CD314 Mouse anti-Human, PE, Clone: 1D11, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB561815-Each-of-1 In Stock ₹ 11,858.62

BDB561815 - Each of 1

₹ 11,858.62

In Stock

Quantity

1

Base Price: ₹ 11,858.62

GST (18%): ₹ 2,134.552

Total Price: ₹ 13,993.172

Antigen

CD314

Classification

Monoclonal

Concentration

0.2mg/mL

Description

CD314; KLRK1; KLR; NKG2D; NKG2-D; NK cell receptor D

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

1D11

Conjugate

PE

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

NKL cells

Quantity

25 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The 1D11 monoclonal antibody specifically binds to NKG2D, a 42 kDa type II transmembrane glycoprotein that is also known as CD314 and KLRK1
  • NKG2D is a member of the C-type lectin family and is expressed on human NK cells
  • This activating receptor binds strongly to several ligands including MICA and MICB and ULBP-1, -2, and -3 proteins that are expressed by different target cell types
  • Different from natural cytotoxicity receptor (NCR), NKG2D expression is not confined to NK cells
  • It is also expressed on virtually all TCR γ/δ+ and CD8+TCR α/β+ T cells
  • NKG2D functions as a triggering receptor involved in natural cytotoxicity mediated by normal NK cells against a variety of tumors or normal target cells
  • Importantly, NKG2D can complement the role of NCR in tumor cell lysis
  • Remarkably, the combined maskings of NCR and NKG2D can reportedly lead to a complete inhibition of NK-mediated lysis of all tumor or normal cells
  • The 1D11 antibody can reportedly block or stimulate the function of NKG2D-positive cells.

Compare Similar Items

Show Difference

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BD Biosciences

BDB561815

--


Antigen:
CD314

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
CD314; KLRK1; KLR; NKG2D; NKG2-D; NK cell receptor D

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
1D11

Conjugate:
PE

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
NKL cells

Quantity:
25 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

BD Biosciences

BDB561816

--


Antigen:
CD33

Classification:
Monoclonal

Concentration:
__

Description:
__

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
WM53 (also known as WM-53)

Conjugate:
PE

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Acute Myeloid Leukemia Blasts

Quantity:
25 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

BD Biosciences

BDB561817

--


Antigen:
CD33

Classification:
Monoclonal

Concentration:
__

Description:
__

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
WM53 (also known as WM-53)

Conjugate:
APC

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Acute Myeloid Leukemia Blasts

Quantity:
25 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

BD Biosciences

BDB561820

--


Antigen:
CD36

Classification:
Monoclonal

Concentration:
__

Description:
__

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgM κ

Applications:
Flow Cytometry

Clone:
CB38 (also known as NL07)

Conjugate:
FITC

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human Platelet Extracts

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.