BDB562365
CD314/NKG2D Mouse anti-Human, PE-Cy7, Clone: 1D11, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB562365-Each-of-1 | In Stock | ₹ 20,826.00 |
BDB562365 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 20,826.00
GST (18%): ₹ 3,748.68
Total Price: ₹ 24,574.68
Antigen
CD314
Classification
Monoclonal
Conjugate
PE-Cyanine7
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
NKL cells
Quantity
50 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
1D11
Description
CD314; KLRK1; KLR; NKG2D; NKG2-D; NK cell receptor D
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- The 1D11 monoclonal antibody specifically binds to NKG2D, a 42 kDa type II transmembrane glycoprotein that is also known as CD314 and KLRK1
- NKG2D is a member of the C-type lectin family and is expressed on human NK cells
- This activating receptor binds strongly to several ligands including MICA and MICB and ULBP-1, -2, and -3 proteins that are expressed by different target cell types
- Different from natural cytotoxicity receptor (NCR), NKG2D expression is not confined to NK cells
- It is also expres sed on virtually all TCR γ/δ+ and CD8+TCR α/β+ T cells
- NKG2D functions as a triggering receptor involved in natural cytotoxicity mediated by normal NK cells against a variety of tumor s or normal target cells
- Importantly, NKG2D can complement the role of NCR in tumor cell lysis
- Remarkably, the combined maskings of NCR and NKG2D can reportedly lead to a complete inhibition of NK-mediated lysis of all tumor or normal cells
- The 1D11 antibody can reportedly block or stimulate the function of NKG2D-positive cells.
Compare Similar Items
Show Difference
Antigen: CD314
Classification: Monoclonal
Conjugate: PE-Cyanine7
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: NKL cells
Quantity: 50 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 1D11
Description: CD314; KLRK1; KLR; NKG2D; NKG2-D; NK cell receptor D
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD314
Classification:
Monoclonal
Conjugate:
PE-Cyanine7
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
NKL cells
Quantity:
50 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
1D11
Description:
CD314; KLRK1; KLR; NKG2D; NKG2-D; NK cell receptor D
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: I-A/I-E
Classification: Monoclonal
Conjugate: Violet Fluor 500 (V500)
Formulation: Aqueous buffered solution containing protein stabilizer, glycerol and ≤0.09% sodium azide.
Immunogen: Activated C57BL/6 mouse spleen cells
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: M5/114.15.2
Description: M5/114; H-2I; Ia Ag; I-Ab, I-Ad, I-Aq, I-Ed, and I-Ek MHC class II alloAgs
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2b κ
Antigen:
I-A/I-E
Classification:
Monoclonal
Conjugate:
Violet Fluor 500 (V500)
Formulation:
Aqueous buffered solution containing protein stabilizer, glycerol and ≤0.09% sodium azide.
Immunogen:
Activated C57BL/6 mouse spleen cells
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
M5/114.15.2
Description:
M5/114; H-2I; Ia Ag; I-Ab, I-Ad, I-Aq, I-Ed, and I-Ek MHC class II alloAgs
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2b κ
Antigen: I-A/I-E
Classification: Monoclonal
Conjugate: Alexa Fluor 647
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Activated C57BL/6 mouse spleen cells
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: M5/114.15.2
Description: M5/114; H-2I; Ia Ag; I-Ab, I-Ad, I-Aq, I-Ed, and I-Ek MHC class II alloAgs
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2b κ
Antigen:
I-A/I-E
Classification:
Monoclonal
Conjugate:
Alexa Fluor 647
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Activated C57BL/6 mouse spleen cells
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
M5/114.15.2
Description:
M5/114; H-2I; Ia Ag; I-Ab, I-Ad, I-Aq, I-Ed, and I-Ek MHC class II alloAgs
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2b κ
Antigen: CD15
Classification: Monoclonal
Conjugate: Alexa Fluor 647
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: __
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: W6D3
Description: 3-fucosyl-N-acetyllactosamine; 3-FAL
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD15
Classification:
Monoclonal
Conjugate:
Alexa Fluor 647
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
__
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
W6D3
Description:
3-fucosyl-N-acetyllactosamine; 3-FAL
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ