BDB562364

CD314/NKG2D Mouse anti-Human, PerCP-Cy5.5, Clone: 1D11, BD

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB562364-Each-of-1 In Stock ₹ 20,705.52

BDB562364 - Each of 1

₹ 20,705.52

In Stock

Quantity

1

Base Price: ₹ 20,705.52

GST (18%): ₹ 3,726.994

Total Price: ₹ 24,432.514

Antigen

CD314

Classification

Monoclonal

Conjugate

PerCP-Cyanine5.5

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

NKL cells

Quantity

50 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

1D11

Description

CD314; KLRK1; KLR; NKG2D; NKG2-D; NK cell receptor D

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

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Description

  • The 1D11 monoclonal antibody specifically binds to NKG2D, a 42 kDa type II transmembrane glycoprotein that is also known as CD314 and KLRK1
  • NKG2D is a member of the C-type lectin family and is expressed on human NK cells
  • This activating receptor binds strongly to several ligands including MICA and MICB and ULBP-1, -2, and -3 proteins that are expressed by different target cell types
  • Different from natural cytotoxicity receptor (NCR), NKG2D expression is not confined to NK cells
  • It is also expressed on virtually all TCR γ/δ+ and CD8+TCR α/β+ T cells
  • NKG2D functions as a triggering receptor involved in natural cytotoxicity mediated by normal NK cells against a variety of tumors or normal target cells
  • Importantly, NKG2D can complement the role of NCR in tumor cell lysis
  • Remarkably, the combined maskings of NCR and NKG2D can reportedly lead to a complete inhibition of NK-mediated lysis of all tumor or normal cells
  • The 1D11 antibody can reportedly block or stimulate the function of NKG2D-positive cells.

Compare Similar Items

Show Difference

Img

BD Biosciences

BDB562364

--


Antigen:
CD314

Classification:
Monoclonal

Conjugate:
PerCP-Cyanine5.5

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
NKL cells

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
1D11

Description:
CD314; KLRK1; KLR; NKG2D; NKG2-D; NK cell receptor D

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Img

BD Biosciences

BDB562365

--


Antigen:
CD314

Classification:
Monoclonal

Conjugate:
PE-Cyanine7

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
NKL cells

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
1D11

Description:
CD314; KLRK1; KLR; NKG2D; NKG2-D; NK cell receptor D

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Img

BD Biosciences

BDB562366

--


Antigen:
I-A/I-E

Classification:
Monoclonal

Conjugate:
Violet Fluor 500 (V500)

Formulation:
Aqueous buffered solution containing protein stabilizer, glycerol and ≤0.09% sodium azide.

Immunogen:
Activated C57BL/6 mouse spleen cells

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
M5/114.15.2

Description:
M5/114; H-2I; Ia Ag; I-Ab, I-Ad, I-Aq, I-Ed, and I-Ek MHC class II alloAgs

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2b κ

Img

BD Biosciences

BDB562367

--


Antigen:
I-A/I-E

Classification:
Monoclonal

Conjugate:
Alexa Fluor 647

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Activated C57BL/6 mouse spleen cells

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
M5/114.15.2

Description:
M5/114; H-2I; Ia Ag; I-Ab, I-Ad, I-Aq, I-Ed, and I-Ek MHC class II alloAgs

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2b κ