BDB562347
CD314 Rat anti-Mouse, APC, Clone: CX5, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB562347-Each-of-1 | In Stock | ₹ 22,074.48 |
BDB562347 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 22,074.48
GST (18%): ₹ 3,973.406
Total Price: ₹ 26,047.886
Antigen
CD314
Classification
Monoclonal
Concentration
0.2mg/mL
Description
Klrk1; NKG2D; NKG2-D; NK cell receptor D; Natural killer cell group 2D
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Mouse
Isotype
IgG1
Applications
Flow Cytometry
Clone
CX5
Conjugate
APC
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Purified Mouse NKG2D protein
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- The CX5 monoclonal antibody specifically binds to NKG2D, also known as CD314
- NKG2D is a lectin-like receptor that is detected on resting and IL-2-activated NK cells, activated CD8-positive T lymphocytes, and LPS-activated macrophages, but not on resting T cells or unstimulated macrophages
- NKG2D has little homology to the other members of the NKG2 family, NKG2A, C, and E, and does not form heterodimers with CD94
- On NK cells, NKG2D is an activating receptor that associates with DAP10, an adapter protein that stimulates the PI3 kinase pathway
- An isoform of mouse NKG2D can also associate with the signaling adapter protein DAP12, also known as KARAP ( K iller cell- A ssociated R eceptor- olypeptide), that activates the Syk and ZAP70 tyrosine kinases
- On cytotoxic T cells, NKG2D is a co-stimulatory receptor that associates with DAP10
- The ligands for NKG2D include the minor histocompatibility antigen H60, MULT1 ( M urine UL 16-binding protein- L ike T ranscript ), and the five retinoic acid-inducible proteins Rae-1 a , b , g , d and e
- Interactions of NKG2D with its ligands are involved in the regulation of innate and immune cytotoxic responses to tumor and pathogen-infected cells and in diabetes progression in the NOD mouse
- The CX5 mAb blocks the binding of NKG2D to its ligands.
Compare Similar Items
Show Difference
Antigen: CD314
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: Klrk1; NKG2D; NKG2-D; NK cell receptor D; Natural killer cell group 2D
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG1
Applications: Flow Cytometry
Clone: CX5
Conjugate: APC
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Purified Mouse NKG2D protein
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD314
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
Klrk1; NKG2D; NKG2-D; NK cell receptor D; Natural killer cell group 2D
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG1
Applications:
Flow Cytometry
Clone:
CX5
Conjugate:
APC
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Purified Mouse NKG2D protein
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: Erythroid Cells
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: __
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Rat
Isotype: IgM κ
Applications: Flow Cytometry
Clone: HIS49
Conjugate: APC
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen: Rat bone marrow cells
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
Erythroid Cells
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
__
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Rat
Isotype:
IgM κ
Applications:
Flow Cytometry
Clone:
HIS49
Conjugate:
APC
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen:
Rat bone marrow cells
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD94
Classification: Monoclonal
Concentration: __
Description: KLRD1; Killer cell lectin-like receptor subfamily D member 1; KP43
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: HP-3D9
Conjugate: PerCP-Cyanine5.5
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Human NK Cells
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD94
Classification:
Monoclonal
Concentration:
__
Description:
KLRD1; Killer cell lectin-like receptor subfamily D member 1; KP43
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
HP-3D9
Conjugate:
PerCP-Cyanine5.5
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Human NK Cells
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD160
Classification: Monoclonal
Concentration: __
Description: BY55; BY55 antigen; NK1; NK28
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgM
Applications: Flow Cytometry
Clone: BY55
Conjugate: Alexa Fluor 647
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen: Human YT2C2 NK cell line
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD160
Classification:
Monoclonal
Concentration:
__
Description:
BY55; BY55 antigen; NK1; NK28
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgM
Applications:
Flow Cytometry
Clone:
BY55
Conjugate:
Alexa Fluor 647
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen:
Human YT2C2 NK cell line
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.