BDB564454
CD11b Rat anti-Mouse, BB515, Clone: M1/70, BD
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB564454-Each-of-1 | In Stock | ₹ 15,229.68 |
BDB564454 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 15,229.68
GST (18%): ₹ 2,741.342
Total Price: ₹ 17,971.022
Antigen
CD11b
Classification
Monoclonal
Concentration
0.2mg/mL
Description
Itgam; Integrin alpha-M; Ly-40; Mac-1a; Mac-1 alpha; CR3A; CR-3 alpha chain
Immunogen
Mouse Splenic Cells
Quantity
100 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
M1/70
Conjugate
Brilliant Blue 515 (BB515)
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Mouse
Isotype
IgG2b κ
Description
- The M1/70 monoclonal antibody specifically binds to CD11b, also known as Integrin alpha M (Itgam or αM)
- CD11b is a 170-kDa type 1 transmembrane glycoprotein and belongs to the Integrin alpha chain family
- CD11b serves as the alpha chain of the heterodimeric Mac-1 integrin (CD11b/CD18, αMβ2), also known as complement receptor 3 (CR3)
- Mac-1 mediates adhesion to ICAM-1 (CD54), ICAM-2 (CD102), fibrinogen and binding to C3bi
- Mac-1 is expressed at varying levels on granulocytes, macrophages, myeloid-derived dendritic cells, natural killer cells, microglia, and B-1 B lymphocytes
- Mac-1 expression is rapidly up-regulated on neutrophils after activation, in the same time period that CD62L (L-selectin) is shed from the cell surface
- The M1/70 antibody reportedly blocks cell adherence and C3bi binding but does not block cell-mediated lysis
- Cross-reaction of the M1/70 antibody with CD11b expressed on human monocytes, polymorphonuclear leukocytes, and NK cells has been reported.
Compare Similar Items
Show Difference
Antigen: CD11b
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: Itgam; Integrin alpha-M; Ly-40; Mac-1a; Mac-1 alpha; CR3A; CR-3 alpha chain
Immunogen: Mouse Splenic Cells
Quantity: 100 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: M1/70
Conjugate: Brilliant Blue 515 (BB515)
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2b κ
Antigen:
CD11b
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
Itgam; Integrin alpha-M; Ly-40; Mac-1a; Mac-1 alpha; CR3A; CR-3 alpha chain
Immunogen:
Mouse Splenic Cells
Quantity:
100 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
M1/70
Conjugate:
Brilliant Blue 515 (BB515)
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2b κ
Antigen: CD11b
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: Itgam; Integrin alpha-M; Ly-40; Mac-1a; Mac-1 alpha; CR3A; CR-3 alpha chain
Immunogen: Mouse Splenic Cells
Quantity: 100 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: M1/70
Conjugate: Brilliant Blue 515 (BB515)
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2b κ
Antigen:
CD11b
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
Itgam; Integrin alpha-M; Ly-40; Mac-1a; Mac-1 alpha; CR3A; CR-3 alpha chain
Immunogen:
Mouse Splenic Cells
Quantity:
100 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
M1/70
Conjugate:
Brilliant Blue 515 (BB515)
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2b κ
Antigen: CD19
Classification: Monoclonal
Concentration: __
Description: B4; B-lymphocyte antigen CD19; Leu-12
Immunogen: __
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: HIB19
Conjugate: Brilliant Blue 515 (BB515)
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD19
Classification:
Monoclonal
Concentration:
__
Description:
B4; B-lymphocyte antigen CD19; Leu-12
Immunogen:
__
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
HIB19
Conjugate:
Brilliant Blue 515 (BB515)
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD19
Classification: Monoclonal
Concentration: __
Description: B4; B-lymphocyte antigen CD19; Leu-12
Immunogen: __
Quantity: 25 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: HIB19
Conjugate: Brilliant Blue 515 (BB515)
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD19
Classification:
Monoclonal
Concentration:
__
Description:
B4; B-lymphocyte antigen CD19; Leu-12
Immunogen:
__
Quantity:
25 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
HIB19
Conjugate:
Brilliant Blue 515 (BB515)
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ