BDB564536

CD335 (NKp46) Mouse anti-Human, BB515, Clone: 9E2/NKp46 (also known as 9-E2), BD

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB564536-Each-of-1 In Stock ₹ 27,036.96

BDB564536 - Each of 1

₹ 27,036.96

In Stock

Quantity

1

Base Price: ₹ 27,036.96

GST (18%): ₹ 4,866.653

Total Price: ₹ 31,903.613

Antigen

CD335

Clone

9E2/NKp46 (also known as 9-E2)

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

Classification

Monoclonal

Conjugate

Brilliant Blue 515 (BB515)

Gene Alias

NCR1, NK-p46, hNKp46, LY94, Natural cytotoxicity triggering receptor 1

Immunogen

Human NKp46 Recombinant Protein

Quantity

100 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The 9E2/Nkp46 monoclonal antibody specifically binds to CD335
  • CD335 is also known as the Natural killer cell p46-related protein (NKp46) and the Natural cytotoxicity triggering receptor 1 (NCR1)
  • CD335 is a 46 kDa type I membrane glycoprotein that is expressed on resting and activated NK cells
  • Its extracellular region contains two C2-type, Ig-like domains
  • The transmembrane domain contains a positively charged amino acid (Arg) which could be involved in stabilizing the association with CD3ζ
  • Its intracellular region does not contain immunoreceptor tyrosine-based activating motifs (ITAM), but it is linked to intracytoplasmic transduction machinery by its association with CD3ζ and FcεRIγ adaptor proteins.CD335 along with NKp30 and NKp44 are referred to as natural cytotoxicity receptors (NCR)
  • These receptors play very important roles in cells that kill virus-infected target cells, tumor cells and MHC-class I-unprotected cells
  • The antibody was conjugated to BD Horizon BB515 which was developed exclusively by BD Biosciences
  • With an excitation max of 490 nm and an emission max of 515 nm, BD Horizon BB515 can be excited by the 488 nm laser and detected in a standard FITC set (eg, 530/30nm filter)
  • This dye provides a much brighter alternative to FITC with less spillover into the PE detector
  • BB515 is a dye that was exclusively developed by BD Biosciences as a brighter alternative to FITC
  • This dye is up to seven times brighter than FITC and has less spillover into the PE channel
  • Due to similar excitation and emission properties, BB515, FITC, and Alexa Fluor™ 488 cannot be used simultaneously.

Compare Similar Items

Show Difference

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BD Biosciences

BDB564536

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Antigen:
CD335

Clone:
9E2/NKp46 (also known as 9-E2)

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Classification:
Monoclonal

Conjugate:
Brilliant Blue 515 (BB515)

Gene Alias:
NCR1, NK-p46, hNKp46, LY94, Natural cytotoxicity triggering receptor 1

Immunogen:
Human NKp46 Recombinant Protein

Quantity:
100 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

BD Biosciences

BDB564537

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Antigen:
CD335 (NKp46)

Clone:
9E2/NKp46 (also known as 9-E2)

Formulation:
__

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Classification:
Monoclonal

Conjugate:
Brilliant Blue 515 (BB515)

Gene Alias:
__

Immunogen:
__

Quantity:
25 Tests

Primary or Secondary:
Primary

Content And Storage:
Refrigerate (2 to 8°C)

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BD Biosciences

BDB564545

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Antigen:
CD86

Clone:
2331 (FUN-1)

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Target Species:
Baboon, Cynomolgus, Human, Rhesus Monkey

Isotype:
IgG1 κ

Classification:
Monoclonal

Conjugate:
Brilliant Blue 515 (BB515)

Gene Alias:
B7.2; B7-2; B-lymphocyte activation antigen B7-2; B70; BU63; CD28LG2; LAB72

Immunogen:
Human HBL-1 Cell Line

Quantity:
25 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with BD Horizon™ BB515 under optimum conditions and unconjugated antibody was removed.

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BD Biosciences

BDB564552

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Antigen:
CD45RA

Clone:
HI100

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2b κ

Classification:
Monoclonal

Conjugate:
Brilliant Blue 515 (BB515)

Gene Alias:
CD45R; PTPRC; LCA; Leukocyte common antigen

Immunogen:
__

Quantity:
100 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with BD Horizon™ BB515 under optimum conditions and unconjugated antibody was removed.