BDB564675

CD218a (IL-18Rα) Mouse anti-Human, PE, Clone: H44, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB564675-Each-of-1 In Stock ₹ 20,021.04

BDB564675 - Each of 1

₹ 20,021.04

In Stock

Quantity

1

Base Price: ₹ 20,021.04

GST (18%): ₹ 3,603.787

Total Price: ₹ 23,624.827

Antigen

CD218a (IL-18Rα)

Classification

Monoclonal

Conjugate

PE

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Human NK Cell Line

Quantity

50 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

H44

Description

IL-1Rrp; IL1RRP; IL18RA; IL-18Rα; IL-18R1; IL-18R-1; IL18R1

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

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Description

  • The H44 monoclonal antibody specifically binds to CD218a, which is also known as Interleukin-18 receptor 1 (IL-18R1), IL-18 Receptor alpha (IL-18R α ) and IL1 Receptor-related protein (IL-1Rrp)
  • CD218a is a type I transmembrane glycoprotein that associates with CD218b (IL-18R β ) subunit to form the functional IL-18 Receptor Complex
  • Both subunits belong to the IL-1R family
  • The IL-18R α chain is responsible for extracellular IL-18 binding whereas the IL-18R β subunit is involved in intracellular signaling through the NF κ B pathway
  • CD218a is expressed on a variety of cells including T cells, NK cells, macrophages, granulocytes, keratinocytes, endothelial cells, and smooth muscle cells
  • CD218a expression is induced weakly in T cells by IL-12 treatment and moderately by phytohemagglutinin (PHA) stimulation
  • Costimulation with both IL-12 and PHA induces optimal CD218a expression on CD4+ T cells, CD8+ T cells, and CD56+ NK cells
  • The IL-18/IL-18R Complex plays important roles in adaptive immunity as well as innate immune responses and autoimmunity
  • H44 reportedly neutralized the biological activity of recombinant human IL-18 protein.

Compare Similar Items

Show Difference

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BD Biosciences

BDB564675

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Antigen:
CD218a (IL-18Rα)

Classification:
Monoclonal

Conjugate:
PE

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human NK Cell Line

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
H44

Description:
IL-1Rrp; IL1RRP; IL18RA; IL-18Rα; IL-18R1; IL-18R-1; IL18R1

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

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BD Biosciences

BDB564679

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Antigen:
CD66b

Classification:
Monoclonal

Conjugate:
Brilliant Blue 515 (BB515)

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide

Immunogen:
Human Granulocytes

Quantity:
100 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
G10F5

Description:
CEACAM8; CGM6; NCA-95

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgM κ

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BD Biosciences

BDB564680

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Antigen:
IgM

Classification:
Monoclonal

Conjugate:
Brilliant Blue 515 (BB515)

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide

Immunogen:
TNP-Keyhole Limpet Hemocyanin

Quantity:
50 μg

Primary or Secondary:
Secondary

Content And Storage:
4°C, protect from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
G155-228

Description:
__

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
__

Target Species:
__

Isotype:
IgM κ

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Antigen:
CD122

Classification:
Monoclonal

Conjugate:
Brilliant Blue 515 (BB515)

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide

Immunogen:
Human YTS Cell Line

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
Mik-β3

Description:
IL2RB; IL-2Rβ; IL-2R subunit beta; IL-2RB; IL15RB; IL-2/15Rb; IL-2R p75

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ