BDB565326

LAIR-1 Mouse anti-Human, Alexa Fluor 647, Clone: DX26, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB565326-Each-of-1 In Stock ₹ 24,299.04

BDB565326 - Each of 1

₹ 24,299.04

In Stock

Quantity

1

Base Price: ₹ 24,299.04

GST (18%): ₹ 4,373.827

Total Price: ₹ 28,672.867

Antigen

LAIR-1

Classification

Monoclonal

Conjugate

Alexa Fluor 647

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Human NK Cell Clone

Quantity

50 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

DX26

Description

CD305; LAIR1; hLAIR1; Leukocyte-associated Ig-like receptor 1

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

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Description

  • The DX26 monoclonal antibody specifically binds to Leukocyte-associated immunoglobulin-like receptor 1 (LAIR-1/ hLAIR1/Leukocyte-associated Ig-like receptor 1) that is encoded by LAIR1, and also known as, CD305
  • LAIR-1 is a ∽32 kDa type I transmembrane glycoprotein with a single immunoglobulin-like domain and a cytoplasmic tail containing two immune receptor tyrosine-based inhibitory (ITIM) motifs
  • LAIR-1 is expressed on T cells, B cells, NK cells, monocytes, and dendritic cells
  • LAIR-1 recruits SHP-1 and SHP-2 tyrosine phosphatases upon activation
  • Crosslinking of the LAIR-1 expressed on T cells or NK cells can result in strong inhibition of cell-mediated cytotoxicity
  • Although it is structurally related to human killer cell inhibitory receptors, LAIR-1 does not appear to recognize MHC class I molecules and thus represents a novel MHC class I-independent mechanism of NK cell regulation.

Compare Similar Items

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Img

BD Biosciences

BDB565326

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Antigen:
LAIR-1

Classification:
Monoclonal

Conjugate:
Alexa Fluor 647

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human NK Cell Clone

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
DX26

Description:
CD305; LAIR1; hLAIR1; Leukocyte-associated Ig-like receptor 1

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Img

BD Biosciences

BDB565331

--


Antigen:
Intgrin β7

Classification:
Monoclonal

Conjugate:
Brilliant Blue 515 (BB515)

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Mouse T lymphoma line TK1

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
FIB504

Description:
Itgb7; Integrin β7; Integrin beta 7; ITB7; Ly-69; Ly69

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse

Isotype:
IgG2a κ

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BD Biosciences

BDB565332

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Antigen:
HLA-ABC

Classification:
Monoclonal

Conjugate:
Brilliant Violet 421

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
__

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
G46-2.6

Description:
Major histocompatibility complex, class I, A,B,C; HLA class I A,B,C

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Baboon, Cynomolgus, Human, Rhesus Monkey

Isotype:
IgG1 κ

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BD Biosciences

BDB565333

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Antigen:
HLA-ABC

Classification:
Monoclonal

Conjugate:
Brilliant Violet 711

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
__

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
G46-2.6

Description:
Major histocompatibility complex, class I, A,B,C; HLA class I A,B,C

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Baboon, Cynomolgus, Human, Rhesus Monkey

Isotype:
IgG1 κ