BDB565163

IL-17A Mouse anti-Human, APC-R700, Clone: N49-653, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB565163-Each-of-1 In Stock ₹ 29,774.88

BDB565163 - Each of 1

₹ 29,774.88

In Stock

Quantity

1

Base Price: ₹ 29,774.88

GST (18%): ₹ 5,359.478

Total Price: ₹ 35,134.358

Antigen

IL-17A

Classification

Monoclonal

Conjugate

APC-R700

Formulation

Aqueous buffered solution containing BSA, protein stabilizer, glycerol and ≤0.09% sodium azide.

Immunogen

Human IL-17A Recombinant Protein

Quantity

50 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry, Immunocytochemistry

Clone

N49-653

Description

IL-17; CTLA8; Cytotoxic T-lymphocyte-associated serine esterase 8

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

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Description

  • Human IL-17A, also known as IL-17, is a proinflammatory cytokine that is encoded by the IL17A gene in chromosome 6
  • IL-17A is produced as a disulfide-linked homodimer comprised of two mature 136-amino acid polypeptides
  • It is a member of the IL-17 family of structurally related cytokines, designated IL-17A through IL-17F
  • Activated memory T cells, especially Th17 cells (specialized IL-17A-producing CD4+ T cells distinct from Th1 and Th2 cells) produce IL-17 and provide protective immunity against pathogens
  • Activated CD8+ T cells, γδ T cells, NK cells and neutrophils can also be activated to produce IL-17A
  • IL-17A binds to and exerts its biological activity through IL-17 receptors (IL-17R) that are expressed by a variety of target cells including fibroblasts, epithelial and endothelial cells, monocytes/macrophages and mast cells
  • The ubiquitous IL-17R expression pattern may explain the broad tissue responsiveness to IL-17
  • IL-17 induces stromal cells to secrete cytokines and chemokines involved in inflammatory and hematopoietic processes
  • For example, IL-17 induces fibroblasts to produce IL-6, IL-8, G-CSF and express increased surface ICAM-1
  • The N49-653 antibody reacts with human IL-17A
  • This antibody was conjugated to BD Horizon APC-R700, which has been developed exclusively by BD Biosciences as a better alternative to Alexa Fluor™ 700
  • APC-R700 excites and emits at similar wavelengths to Alexa Fluor™ 700 yet exhibits significantly improved brightness
  • This dye can be excited by the red laser and detected with the same filter set as Alexa Fluor™ (eg, 730/45-nm filter).

Compare Similar Items

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BD Biosciences

BDB565163

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Antigen:
IL-17A

Classification:
Monoclonal

Conjugate:
APC-R700

Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, glycerol and ≤0.09% sodium azide.

Immunogen:
Human IL-17A Recombinant Protein

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry, Immunocytochemistry

Clone:
N49-653

Description:
IL-17; CTLA8; Cytotoxic T-lymphocyte-associated serine esterase 8

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Img

BD Biosciences

BDB565165

--


Antigen:
CD8

Classification:
Monoclonal

Conjugate:
APC-R700

Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, glycerol and ≤0.09% sodium azide.

Immunogen:
Human CD8a

Quantity:
100 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with BD Horizon APC-R700 under optimum conditions, and unconjugated antibody and free BD Horizon APC-R700 were removed.

Applications:
Flow Cytometry

Clone:
RPA-T8

Description:
__

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Target Species:
Human, Rhesus Monkey, Cynomolgus, Baboon

Isotype:
IgG1 κ

Img

BD Biosciences

BDB565166

--


Antigen:
CD8

Classification:
Monoclonal

Conjugate:
APC-R700

Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, glycerol, and ≤0.09% sodium azide.

Immunogen:
Human CD8a

Quantity:
25 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
RPA-T8

Description:
CD8α; CD8A; CD8 alpha; Leu2; MAL; T8; p32

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Baboon, Cynomolgus, Human, Rhesus Monkey

Isotype:
IgG1 κ

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BD Biosciences

BDB565168

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Antigen:
TIGIT

Classification:
Monoclonal

Conjugate:
PE

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide

Immunogen:
Mouse TIGIT Recombinant Protein

Quantity:
0.1 mg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
1G9

Description:
Tigit; Vstm3; T cell immunoreceptor with Ig and ITIM domains

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG1 κ