BDB565163
IL-17A Mouse anti-Human, APC-R700, Clone: N49-653, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB565163-Each-of-1 | In Stock | ₹ 29,774.88 |
BDB565163 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 29,774.88
GST (18%): ₹ 5,359.478
Total Price: ₹ 35,134.358
Antigen
IL-17A
Classification
Monoclonal
Conjugate
APC-R700
Formulation
Aqueous buffered solution containing BSA, protein stabilizer, glycerol and ≤0.09% sodium azide.
Immunogen
Human IL-17A Recombinant Protein
Quantity
50 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry, Immunocytochemistry
Clone
N49-653
Description
IL-17; CTLA8; Cytotoxic T-lymphocyte-associated serine esterase 8
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- Human IL-17A, also known as IL-17, is a proinflammatory cytokine that is encoded by the IL17A gene in chromosome 6
- IL-17A is produced as a disulfide-linked homodimer comprised of two mature 136-amino acid polypeptides
- It is a member of the IL-17 family of structurally related cytokines, designated IL-17A through IL-17F
- Activated memory T cells, especially Th17 cells (specialized IL-17A-producing CD4+ T cells distinct from Th1 and Th2 cells) produce IL-17 and provide protective immunity against pathogens
- Activated CD8+ T cells, γδ T cells, NK cells and neutrophils can also be activated to produce IL-17A
- IL-17A binds to and exerts its biological activity through IL-17 receptors (IL-17R) that are expressed by a variety of target cells including fibroblasts, epithelial and endothelial cells, monocytes/macrophages and mast cells
- The ubiquitous IL-17R expression pattern may explain the broad tissue responsiveness to IL-17
- IL-17 induces stromal cells to secrete cytokines and chemokines involved in inflammatory and hematopoietic processes
- For example, IL-17 induces fibroblasts to produce IL-6, IL-8, G-CSF and express increased surface ICAM-1
- The N49-653 antibody reacts with human IL-17A
- This antibody was conjugated to BD Horizon APC-R700, which has been developed exclusively by BD Biosciences as a better alternative to Alexa Fluor™ 700
- APC-R700 excites and emits at similar wavelengths to Alexa Fluor™ 700 yet exhibits significantly improved brightness
- This dye can be excited by the red laser and detected with the same filter set as Alexa Fluor™ (eg, 730/45-nm filter).
Compare Similar Items
Show Difference
Antigen: IL-17A
Classification: Monoclonal
Conjugate: APC-R700
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, glycerol and ≤0.09% sodium azide.
Immunogen: Human IL-17A Recombinant Protein
Quantity: 50 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry, Immunocytochemistry
Clone: N49-653
Description: IL-17; CTLA8; Cytotoxic T-lymphocyte-associated serine esterase 8
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
IL-17A
Classification:
Monoclonal
Conjugate:
APC-R700
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, glycerol and ≤0.09% sodium azide.
Immunogen:
Human IL-17A Recombinant Protein
Quantity:
50 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry, Immunocytochemistry
Clone:
N49-653
Description:
IL-17; CTLA8; Cytotoxic T-lymphocyte-associated serine esterase 8
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD8
Classification: Monoclonal
Conjugate: APC-R700
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, glycerol and ≤0.09% sodium azide.
Immunogen: Human CD8a
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with BD Horizon APC-R700 under optimum conditions, and unconjugated antibody and free BD Horizon APC-R700 were removed.
Applications: Flow Cytometry
Clone: RPA-T8
Description: __
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Target Species: Human, Rhesus Monkey, Cynomolgus, Baboon
Isotype: IgG1 κ
Antigen:
CD8
Classification:
Monoclonal
Conjugate:
APC-R700
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, glycerol and ≤0.09% sodium azide.
Immunogen:
Human CD8a
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with BD Horizon APC-R700 under optimum conditions, and unconjugated antibody and free BD Horizon APC-R700 were removed.
Applications:
Flow Cytometry
Clone:
RPA-T8
Description:
__
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Target Species:
Human, Rhesus Monkey, Cynomolgus, Baboon
Isotype:
IgG1 κ
Antigen: CD8
Classification: Monoclonal
Conjugate: APC-R700
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, glycerol, and ≤0.09% sodium azide.
Immunogen: Human CD8a
Quantity: 25 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: RPA-T8
Description: CD8α; CD8A; CD8 alpha; Leu2; MAL; T8; p32
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Baboon, Cynomolgus, Human, Rhesus Monkey
Isotype: IgG1 κ
Antigen:
CD8
Classification:
Monoclonal
Conjugate:
APC-R700
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, glycerol, and ≤0.09% sodium azide.
Immunogen:
Human CD8a
Quantity:
25 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
RPA-T8
Description:
CD8α; CD8A; CD8 alpha; Leu2; MAL; T8; p32
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Baboon, Cynomolgus, Human, Rhesus Monkey
Isotype:
IgG1 κ
Antigen: TIGIT
Classification: Monoclonal
Conjugate: PE
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide
Immunogen: Mouse TIGIT Recombinant Protein
Quantity: 0.1 mg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 1G9
Description: Tigit; Vstm3; T cell immunoreceptor with Ig and ITIM domains
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG1 κ
Antigen:
TIGIT
Classification:
Monoclonal
Conjugate:
PE
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide
Immunogen:
Mouse TIGIT Recombinant Protein
Quantity:
0.1 mg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
1G9
Description:
Tigit; Vstm3; T cell immunoreceptor with Ig and ITIM domains
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG1 κ