BDB565474

TIGIT Mouse anti-Mouse, APC-R700, Clone: 1G9, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB565474-Each-of-1 In Stock ₹ 22,545.06

BDB565474 - Each of 1

₹ 22,545.06

In Stock

Quantity

1

Base Price: ₹ 22,545.06

GST (18%): ₹ 4,058.111

Total Price: ₹ 26,603.171

Antigen

TIGIT

Classification

Monoclonal

Concentration

0.2mg/mL

Description

Tigit; Vstm3; T cell immunoreceptor with Ig and ITIM domains

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

1G9

Conjugate

APC-R700

Formulation

Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Immunogen

Mouse TIGIT Recombinant Protein

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Description

  • The 1G9 monoclonal antibody specifically binds to T cell immunoreceptor with Ig and ITIM domains (TIGIT) which is also known as, V-set and transmembrane domain-containing protein 3 (Vstm3)
  • TIGIT is a 26 kDa, type I transmembrane glycoprotein that belongs to the poliovirus receptor (PVR) family
  • TIGIT is expressed on activated and memory CD4+ T cells and CD8+ T cells, follicular T helper cells, regulatory T cells, and NK cells
  • Its ligands include the poliovirus receptor (PVR, aka, CD155), poliovirus receptor-related protein 2 (PVRL2, aka, CD112), and poliovirus receptor-related protein 3 (PVRL3, CD113)
  • TIGIT functions as a negative regulator of T cell and NK cell responses including proliferation, cytotoxicity, and the production of proinflammatory cytokines
  • TIGIT-deficient mice are reportedly more susceptible to developing autoimmune diseases in certain model systems
  • This antibody was conjugated to BD Horizon APC-R700, which has been developed exclusively by BD Biosciences as a better alternative to Alexa Fluor™ 700
  • APC-R700 excites and emits at similar wavelengths to Alexa Fluor™ 700 yet exhibits significantly improved brightness
  • This dye can be excited by the red laser and detected with the same filter set as Alexa Fluor™ (eg, 730/45-nm filter).

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BD Biosciences

BDB565474

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Antigen:
TIGIT

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Tigit; Vstm3; T cell immunoreceptor with Ig and ITIM domains

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
1G9

Conjugate:
APC-R700

Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Immunogen:
Mouse TIGIT Recombinant Protein

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

BD Biosciences

BDB565477

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Antigen:
KLRG1

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
__

Host Species:
Hamster

Purification Method:
__

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2 κ

Applications:
Flow Cytometry

Clone:
2F1

Conjugate:
Brilliant Violet 786

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
A-LAK from C57BL/6 mice

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with BD Horizon™ BV786 under optimum conditions, and unconjugated antibody and free BD Horizon™ BV786 were removed.

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BD Biosciences

BDB565480

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Antigen:
CD44

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Pgp-1; Ly-24; H-CAM; HERMES; ECMR-III; Hyaluronate Receptor

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
IM7

Conjugate:
APC-R700

Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Immunogen:
Dexamethasone-induced, SJL mouse spontaneous myeloid leukemia M1 cells myeloid leukemia M1

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
CD3

Classification:
Monoclonal

Concentration:
__

Description:
Vol. Per test: 5μL

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
UCHT1

Conjugate:
Brilliant Violet 786

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human infant thymocytes and peripheral blood lymphocytes from a Sézary Syndrome donor

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with BD Horizon™ BV786 under optimum conditions, and unconjugated antibody and free BD Horizon™ BV786 were removed.