BDB566346
CD366 (TIM-3) Mouse anti-Mouse, PE, Clone: 5D12/TIM-3 (also known as 5D12), BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB566346-Each-of-1 | In Stock | ₹ 24,299.04 |
BDB566346 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 24,299.04
GST (18%): ₹ 4,373.827
Total Price: ₹ 28,672.867
Antigen
CD366 (TIM-3)
Clone
5D12/TIM-3 (also known as 5D12)
Conjugate
PE
Gene Alias
Cd366, T-cell membrane protein, Tim3, TIMD-3, Timd3, HAVcr-2, Havcr2,
Immunogen
Mouse TIM-3 Recombinant Protein
Quantity
100 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification
Monoclonal
Concentration
0.2mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Mouse
Isotype
IgG1 κ
Description
- The 5D12 monoclonal antibody specifically binds to NKp80 which is also known as C-type lectin domain family 5 member C (CLEC5C)
- NKp80 is a single-pass type II transmembrane glycoprotein that contains a C-type lectin extracellular domain and is expressed as a ñ80 kDa disulfide-linked homodimer
- NKp80 is encoded by KLRF1 /(Killer cell lectin-like receptor subfamily F member 1) which maps to the NK-gene complex (NKC)
- NKp80 is expressed on most NK cells, and subsets ofγδ T cellsand effector-memory CD8αβT cells
- NKp80 is not present in rodents
- NKp80 is an activating coreceptor that induces NK cell-mediated cytotoxicity and proinflammatory cytokine (eg, IFN-γand TNF) production upon interaction with its ligand, AICL (Activation induced C type lectin)
- AICL is encoded by CLEC2B /that is selectively expressed on myeloid cells including activated monocytes, macrophages, and granulocytes
- NKp80 can reportedly transduce signals through an atypical hemi-ITAM-like sequence motif and Syk kinase to trigger cellular responses
- R-phycoerythrin (PE) is an accessory photosynthetic pigment found in red algae
- It exists in vitro as a 240-kDa protein with 23 phycoerythrobilin chromophores per molecule
- This makes PE one of the brightest fluorochromes for flow cytometry applications, but its photobleaching properties make it unsuitable for fluorescence microscopy.
Compare Similar Items
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Antigen: CD366 (TIM-3)
Clone: 5D12/TIM-3 (also known as 5D12)
Conjugate: PE
Gene Alias: Cd366, T-cell membrane protein, Tim3, TIMD-3, Timd3, HAVcr-2, Havcr2,
Immunogen: Mouse TIM-3 Recombinant Protein
Quantity: 100 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG1 κ
Antigen:
CD366 (TIM-3)
Clone:
5D12/TIM-3 (also known as 5D12)
Conjugate:
PE
Gene Alias:
Cd366, T-cell membrane protein, Tim3, TIMD-3, Timd3, HAVcr-2, Havcr2,
Immunogen:
Mouse TIM-3 Recombinant Protein
Quantity:
100 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG1 κ
Antigen: IRF-3
Clone: SL-12.1 (also known as SL-12)
Conjugate: Alexa Fluor 647
Gene Alias: Interferon regulatory factor 3, IRF-3, IRF3, IIAE7
Immunogen: Human IRF-3 aa. 56-427 Recombinant Fusion Protein
Quantity: 25 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
IRF-3
Clone:
SL-12.1 (also known as SL-12)
Conjugate:
Alexa Fluor 647
Gene Alias:
Interferon regulatory factor 3, IRF-3, IRF3, IIAE7
Immunogen:
Human IRF-3 aa. 56-427 Recombinant Fusion Protein
Quantity:
25 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: __
Clone: __
Conjugate: __
Gene Alias: __
Immunogen: __
Quantity: 1000 tests
Primary or Secondary: __
Content And Storage: 4°C
Classification: __
Concentration: __
Formulation: __
Host Species: __
Purification Method: __
Regulatory Status: __
Target Species: __
Isotype: __
Antigen:
__
Clone:
__
Conjugate:
__
Gene Alias:
__
Immunogen:
__
Quantity:
1000 tests
Primary or Secondary:
__
Content And Storage:
4°C
Classification:
__
Concentration:
__
Formulation:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Target Species:
__
Isotype:
__
Antigen: CD75/CD75s
Clone: ZB55
Conjugate: Alexa Fluor 647
Gene Alias: CD75/CD75s, CDw75
Immunogen: Human CD32 Peptides
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: __
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgM κ
Antigen:
CD75/CD75s
Clone:
ZB55
Conjugate:
Alexa Fluor 647
Gene Alias:
CD75/CD75s, CDw75
Immunogen:
Human CD32 Peptides
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
__
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgM κ