BDB566373
IRF8 Mouse anti-Human, PE, Clone: U31-644, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB566373-Each-of-1 | In Stock | ₹ 28,534.26 |
BDB566373 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 28,534.26
GST (18%): ₹ 5,136.167
Total Price: ₹ 33,670.427
Antigen
IRF8
Clone
U31-644
Conjugate
PE
Gene Alias
IRF-8, IRF8, ICSBP, H-ICSBP, ICSBP1
Immunogen
Human IRF8 Recombinant Protein
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification
Monoclonal
Concentration
0.2mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Description
- The U31-644 monoclonal antibody specifically recognizes human Interferon regulatory factor 8 (IRF8, Interferon consensus sequence-binding protein, ICSBP or H-ICSBP)
- IRF8 is a ∽50kDa transcription factor that belongs to the interferon (IFN) regulatory factor family which consists of 9 members in humans and mice
- IRF8 is variably expressed in hematopoietic cells including monocytes, macrophages, dendritic cells, and B cells
- IRF8 has a conserved N-terminal DNA-binding domain (DBD) and a divergent C-terminal region that functions as the regulatory domain which specifies interactions between IRF8 and other IRF family members, transcription factors, or cofactors
- IRF8 functions as a transcriptional activator or repressor depending on the formation of heterodimeric DNA binding complexes with these different partners
- IRF8 binds to specific DNA motifs including IFN-stimulated response elements (ISRE) and regulates expression of genes including those that encode IFN-alpha (IFN-α), IFN-beta (IFN-β), and IFN-inducible MHC class I genes
- It functions in innate and adaptive immunity by regulating the effector functions of monocytes/macrophages, B cells and dendritic cell subsets
- IRF8 participates in the induction of Type I IFNs, TNF, IL-6, and IL-12 expression by leucocytes stimulated with ligands for Toll-like receptors and other pattern recognition receptors (PRRs)
- IRF8 is also involved in cell cycle regulations and apoptosis and may play a role in tumorigenesis
- R-phycoerythrin (PE) is an accessory photosynthetic pigment found in red algae
- It exists in vitro as a 240-kDa protein with 23 phycoerythrobilin chromophores per molecule
- This makes PE one of the brightest fluorochromes for flow cytometry applications, but its photobleaching properties make it unsuitable for fluorescence microscopy.
Compare Similar Items
Show Difference
Antigen: IRF8
Clone: U31-644
Conjugate: PE
Gene Alias: IRF-8, IRF8, ICSBP, H-ICSBP, ICSBP1
Immunogen: Human IRF8 Recombinant Protein
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
IRF8
Clone:
U31-644
Conjugate:
PE
Gene Alias:
IRF-8, IRF8, ICSBP, H-ICSBP, ICSBP1
Immunogen:
Human IRF8 Recombinant Protein
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD127
Clone: A7R34
Conjugate: Brilliant Violet 421
Gene Alias: Interleukin-7 receptor alpha chain, IL-7R alpha, IL7RA, IL-7RA, IL-7Rα, Il7
Immunogen: Mouse
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2a κ
Antigen:
CD127
Clone:
A7R34
Conjugate:
Brilliant Violet 421
Gene Alias:
Interleukin-7 receptor alpha chain, IL-7R alpha, IL7RA, IL-7RA, IL-7Rα, Il7
Immunogen:
Mouse
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2a κ
Antigen: SLAMF6 (CD352)
Clone: hSF6.4.20
Conjugate: PE
Gene Alias: SLAMF6, NTBA, NTB-A, NKTB-antigen, SLAM family memb. 6, KALI, SF2000, Ly108
Immunogen: Human SLAMF6 Transfected Cell Line
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: __
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
SLAMF6 (CD352)
Clone:
hSF6.4.20
Conjugate:
PE
Gene Alias:
SLAMF6, NTBA, NTB-A, NKTB-antigen, SLAM family memb. 6, KALI, SF2000, Ly108
Immunogen:
Human SLAMF6 Transfected Cell Line
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
__
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CCR8 (CD198)
Clone: 433H
Conjugate: Brilliant Violet 421
Gene Alias: CCR8, CKR-L1, CKRL1, CMKBR8, CMKBRL2, CY6, GPR-CY6, GPRCY6, MGC129966, MGC1
Immunogen: Human CCR8 Transfected Cell Line
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: __
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2a κ
Antigen:
CCR8 (CD198)
Clone:
433H
Conjugate:
Brilliant Violet 421
Gene Alias:
CCR8, CKR-L1, CKRL1, CMKBR8, CMKBRL2, CY6, GPR-CY6, GPRCY6, MGC129966, MGC1
Immunogen:
Human CCR8 Transfected Cell Line
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
__
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ