BDB566979
Bcl-6 Mouse, anti-Human, R718, Clone: K112-91, BD Horizon™
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB566979-Each-of-1 | In Stock | ₹ 34,566.24 |
BDB566979 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 34,566.24
GST (18%): ₹ 6,221.923
Total Price: ₹ 40,788.163
Antigen
Bcl-6
Classification
Monoclonal
Conjugate
R718
Quantity
100 Tests
Primary or Secondary
Primary
Content And Storage
Refrigerate Upon Arrival
Applications
Flow Cytometry
Clone
K112-91
Host Species
Mouse
Regulatory Status
RUO
Target Species
Human
Form
Liquid
Related Products
Description
- The K112-91 monoclonal antibody specifically binds to Bcl-6
- Bcl-6 was first identified as a proto-oncogene frequently deregulated by chromosomal translocations in non-Hodgkin B-cell lymphomas
- It is a nuclear transcriptional repressor of the BTB/POZ zinc-finger family of transcription factors
- In addition to its roles in cancer, Bcl-6 plays important roles in the differentiation of normal cells including B cells, thymocytes, CD4+ or CD8+ T cells
- Bcl-6 is highly expressed in germinal center B cells, where it promotes the germinal center reaction by inducing proliferation and inhibiting the DNA-damage response
- Bcl-6 has been identified as a key factor in promoting the differentiation of CD4+ follicular T helper (Tfh) cells that are involved in promoting germinal center formation and providing help to B cells
- The interplay of Bcl-6 and another transcriptional repressor, Blimp-1, is thought to be critical in defining the results of both B-cell and T-cell differentiation.
Compare Similar Items
Show Difference
Antigen: Bcl-6
Classification: Monoclonal
Conjugate: R718
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Refrigerate Upon Arrival
Applications: Flow Cytometry
Clone: K112-91
Host Species: Mouse
Regulatory Status: RUO
Target Species: Human
Form: Liquid
Antigen:
Bcl-6
Classification:
Monoclonal
Conjugate:
R718
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Refrigerate Upon Arrival
Applications:
Flow Cytometry
Clone:
K112-91
Host Species:
Mouse
Regulatory Status:
RUO
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Human
Form:
Liquid
Antigen: IL-4
Classification: Monoclonal
Conjugate: R718
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Refrigerate Upon Arrival
Applications: Flow Cytometry
Clone: MP4-25D2
Host Species: Mouse
Regulatory Status: RUO
Target Species: Human
Form: Liquid
Antigen:
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Classification:
Monoclonal
Conjugate:
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Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Refrigerate Upon Arrival
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Flow Cytometry
Clone:
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Antigen: IL-4
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Content And Storage: Refrigerate Upon Arrival
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Clone: MP4-25D2
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Antigen:
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Flow Cytometry
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Antigen: CD13
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