BDB569268

CD25 (IL-2 Receptor α) Mouse anti-Human, RB545, Clone: 2A3, BD Horizon™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB569268-Each-of-1 In Stock ₹ 13,005.12

BDB569268 - Each of 1

₹ 13,005.12

In Stock

Quantity

1

Base Price: ₹ 13,005.12

GST (18%): ₹ 2,340.922

Total Price: ₹ 15,346.042

Antigen

CD25 (IL-2 Receptor α)

Classification

Monoclonal

Conjugate

RB545

Gene Alias

IL-2R; IL2RA; IL-2Rα; TCGFR; TAC antigen; p55

Immunogen

Human Phytohemagglutinin-activated T Cells

Quantity

25 Tests

Primary or Secondary

Primary

Target Species

Human

Form

Purified

Excitation/Emission

Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm

Applications

Flow Cytometry

Clone

2A3

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Gene ID (Entrez)

3559

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.

Isotype

IgG1 κ

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Description

  • The 2A3 monoclonal antibody specifically binds to human CD25, the low-affinity alpha subunit of the Interleukin-2 Receptor (IL- 2Rα)
  • CD25 associates with CD122 (IL-2Rβ chain) and CD132 (common γ chain or γc) to form the high-affinity signal-transducing IL-2R complex
  • CD25 is expressed by subsets of thymocytes and peripheral blood lymphocytes including CD4+CD25+ regulatory T cells and memory T cells
  • CD25 antigen density increases on activated T cells including phytohemagglutinin (PHA)-, concanavalin A (Con A)-, and CD3-activated T lymphocytes
  • High levels of CD25 can be expressed by T lymphocytes from mixed lymphocyte cultures and by human T-lymphocyte leukemia virus (HTLV)-infected T-lymphocyte leukemia lines, for example, HUT-102
  • CD25 can also be expressed by activated B cells and macrophages
  • Recombinant IL-2 blocks the binding of the 2A3 antibody to PHA-activated T lymphocytes
  • CD25 (IL-2 Receptor α) Monoclonal antibody specifically detects CD25 (IL-2 Receptor α) in Human samples
  • It is validated for Flow Cytometry

Compare Similar Items

Show Difference

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BD Biosciences

BDB569268

--


Antigen:
CD25 (IL-2 Receptor α)

Classification:
Monoclonal

Conjugate:
RB545

Gene Alias:
IL-2R; IL2RA; IL-2Rα; TCGFR; TAC antigen; p55

Immunogen:
Human Phytohemagglutinin-activated T Cells

Quantity:
25 Tests

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Excitation/Emission:
Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm

Applications:
Flow Cytometry

Clone:
2A3

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Gene ID (Entrez):
3559

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.

Isotype:
IgG1 κ

Img

BD Biosciences

BDB569269

--


Antigen:
CD123 (IL-3 Receptor α)

Classification:
Monoclonal

Conjugate:
RB545

Gene Alias:
IL3RA; IL-3RA; IL-3Rα; IL-3R-alpha; Interleukin-3 receptor subunit alpha

Immunogen:
Human IL-3Ra-transfected cells

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Excitation/Emission:
Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm

Applications:
Flow Cytometry

Clone:
7G3

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Gene ID (Entrez):
3563

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.

Isotype:
IgG2a κ

Img

BD Biosciences

BDB569270

--


Antigen:
CD123 (IL-3 Receptor α)

Classification:
Monoclonal

Conjugate:
RB545

Gene Alias:
IL3RA; IL-3RA; IL-3Rα; IL-3R-alpha; Interleukin-3 receptor subunit alpha

Immunogen:
Human IL-3Ra-transfected cells

Quantity:
25 Tests

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Excitation/Emission:
Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm

Applications:
Flow Cytometry

Clone:
7G3

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Gene ID (Entrez):
3563

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.

Isotype:
IgG2a κ

Img

BD Biosciences

BDB569271

--


Antigen:
CD197 (CCR7)

Classification:
Monoclonal

Conjugate:
RB545

Gene Alias:
BLR2; CC chemokine receptor 7; CMKBR7; EBI1; EVI1; Epstein-Barr virus induced gene 1; MIP-3 beta receptor

Immunogen:
Human CCR7 Transfected Cell Line

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Excitation/Emission:
Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm

Applications:
Flow Cytometry

Clone:
2-L1-A

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Gene ID (Entrez):
1236

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.

Isotype:
IgG1 κ