BDB610027
Phospholipase Cγ1 Mouse, Unlabeled, Clone: 10/PLCGAMMA, BD
Manufacturer: Fischer Scientific
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Antigen
Phospholipase Cγ1
Classification
Monoclonal
Concentration
250μg/mL
Formulation
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen
Cow PLCγ1 N-terminal region Peptide
Quantity
50 μg
Research Discipline
Cell Biology
Target Species
Canine, Chicken, Human, Mouse, Rat
Isotype
IgG1
Applications
Western Blot
Clone
10/PLCGAMMA
Conjugate
Unconjugated
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at -20°C.
Related Products
Description
- Description The Phospholipase C (PLC) isozymes hydrolyze phosphatidyl inositol biphosphate to inositol triphosphate and diacylglycerol
- The former causes release of calcium from the endoplasmic reticulum, while the latter is an activator of Protein Kinase C
- Within the PLC family, PLCγ is the only member that contains SH2 and SH3 domains
- These domains enable it to interact with receptor tyrosine kinases and become enzymatically activated via phosphorylation
- It exists as two isoforms: 1) PLCγ 1, which is ubiquitously expressed, and 2) PLCγ 2, found primarily in the lymphoid system
- PLCγ is essential for growth factor-induced cell motility and mitogenesis
- PLCγ 1 null mice exhibit retarded embryonic growth and lethality in midgestation
- Overexpression of PLCγ is evident in several forms of cancer, and it has been identified as a key mediator of PDGF-dependent cellular transformation
- Thus regulation of PLCγ activity by growth factors is involved in cell growth and transformation.
Compare Similar Items
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Antigen: Phospholipase Cγ1
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Cow PLCγ1 N-terminal region Peptide
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Canine, Chicken, Human, Mouse, Rat
Isotype: IgG1
Applications: Western Blot
Clone: 10/PLCGAMMA
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
Phospholipase Cγ1
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Cow PLCγ1 N-terminal region Peptide
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Canine, Chicken, Human, Mouse, Rat
Isotype:
IgG1
Applications:
Western Blot
Clone:
10/PLCGAMMA
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: Phospholipase Cγ1
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Cow PLCγ1 aa. 82 to 100
Quantity: 150 μg
Research Discipline: Cell Biology
Target Species: Canine, Chicken, Human, Mouse, Rat
Isotype: IgG1
Applications: Western Blot
Clone: 10/PLCGAMMA
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
Phospholipase Cγ1
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Cow PLCγ1 aa. 82 to 100
Quantity:
150 μg
Research Discipline:
Cell Biology
Target Species:
Canine, Chicken, Human, Mouse, Rat
Isotype:
IgG1
Applications:
Western Blot
Clone:
10/PLCGAMMA
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: ERK1
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Rat ERK1 aa. 325 to 345
Quantity: 150 μg
Research Discipline: Cell Biology
Target Species: Canine, Chicken, Frog, Human, Mouse, Rat
Isotype: IgG1
Applications: Western Blot
Clone: MK12
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
ERK1
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Rat ERK1 aa. 325 to 345
Quantity:
150 μg
Research Discipline:
Cell Biology
Target Species:
Canine, Chicken, Frog, Human, Mouse, Rat
Isotype:
IgG1
Applications:
Western Blot
Clone:
MK12
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: Crk
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Human Crk aa. 102 to 304
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Bovine, Canine, Chicken, Frog, Human, Mouse, Rat
Isotype: IgG2a
Applications: Western Blot
Clone: 22
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
Crk
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Human Crk aa. 102 to 304
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Bovine, Canine, Chicken, Frog, Human, Mouse, Rat
Isotype:
IgG2a
Applications:
Western Blot
Clone:
22
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.