BDB610028

Phospholipase Cγ1 Mouse, Unlabeled, Clone: 10/PLCGAMMA, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB610028-Each-of-1 In Stock ₹ 47,571.36

BDB610028 - Each of 1

₹ 47,571.36

In Stock

Quantity

1

Base Price: ₹ 47,571.36

GST (18%): ₹ 8,562.845

Total Price: ₹ 56,134.205

Antigen

Phospholipase Cγ1

Classification

Monoclonal

Concentration

250μg/mL

Formulation

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen

Cow PLCγ1 aa. 82 to 100

Quantity

150 μg

Research Discipline

Cell Biology

Target Species

Canine, Chicken, Human, Mouse, Rat

Isotype

IgG1

Applications

Western Blot

Clone

10/PLCGAMMA

Conjugate

Unconjugated

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

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Description

  • Description The Phospholipase C (PLC) isozymes hydrolyze phosphatidyl inositol biphosphate to inositol triphosphate and diacylglycerol
  • The former causes release of calcium from the endoplasmic reticulum, while the latter is an activator of Protein Kinase C
  • Within the PLC family, PLCγ is the only member that contains SH2 and SH3 domains
  • These domains enable it to interact with receptor tyrosine kinases and become enzymatically activated via phosphorylation
  • It exists as two isoforms: 1) PLCγ 1, which is ubiquitously expressed, and 2) PLCγ 2, found primarily in the lymphoid system
  • PLCγ is essential for growth factor-induced cell motility and mitogenesis
  • PLCγ 1 null mice exhibit retarded embryonic growth and lethality in midgestation
  • Overexpression of PLCγ is evident in several forms of cancer, and it has been identified as a key mediator of PDGF-dependent cellular transformation
  • Thus regulation of PLCγ activity by growth factors is involved in cell growth and transformation.

Compare Similar Items

Show Difference

Img

Fischer Scientific

BDB610028

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Antigen:
Phospholipase Cγ1

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Cow PLCγ1 aa. 82 to 100

Quantity:
150 μg

Research Discipline:
Cell Biology

Target Species:
Canine, Chicken, Human, Mouse, Rat

Isotype:
IgG1

Applications:
Western Blot

Clone:
10/PLCGAMMA

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

Img

BD Biosciences

BDB610031

--


Antigen:
ERK1

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Rat ERK1 aa. 325 to 345

Quantity:
150 μg

Research Discipline:
Cell Biology

Target Species:
Canine, Chicken, Frog, Human, Mouse, Rat

Isotype:
IgG1

Applications:
Western Blot

Clone:
MK12

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

Img

Fischer Scientific

BDB610035

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Antigen:
Crk

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Human Crk aa. 102 to 304

Quantity:
50 μg

Research Discipline:
Cell Biology

Target Species:
Bovine, Canine, Chicken, Frog, Human, Mouse, Rat

Isotype:
IgG2a

Applications:
Western Blot

Clone:
22

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

Img

Fischer Scientific

BDB610036

--


Antigen:
Crk

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Human Crk aa. 102 to 304

Quantity:
150 μg

Research Discipline:
Cell Biology

Target Species:
Bovine, Canine, Chicken, Frog, Human, Mouse, Rat

Isotype:
IgG2a

Applications:
Western Blot

Clone:
22

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.