BDB610202

GSK-3β Mouse, Unlabeled, Clone: 7, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB610202-Each-of-1 In Stock ₹ 47,571.36

BDB610202 - Each of 1

₹ 47,571.36

In Stock

Quantity

1

Base Price: ₹ 47,571.36

GST (18%): ₹ 8,562.845

Total Price: ₹ 56,134.205

Antigen

GSK-3β

Classification

Monoclonal

Concentration

250μg/mL

Formulation

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen

Rat GSK-3β aa. 1-160

Quantity

150 μg

Research Discipline

Cell Biology

Target Species

Canine, Chicken, Human, Mouse, Rat

Isotype

IgG1

Applications

Western Blot

Clone

7

Conjugate

Unconjugated

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

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Description

  • Glycogen Synthase Kinase-3β (GSK-3β) is a serine/threonine kinase that affects glycogen metabolism by phosphorylating and, thus, down-regulating the activity of muscle glycogen synthase
  • GSK-3β is identical to the Tau Protein Kinase 1 (TPK 1) which plays a role in the formation of the histopathological lesions of Alzheimer's disease (AD)
  • In AD, many neurons contain intracytoplasmic neurofibrillary tangles (NFT) that are composed of ubiquitin and highly phosphorylated tau proteins, members of a family of microtubule-assocaited phosphoproteins
  • Phosphorylation of the tau proteins by GSK-3β converts them into paired helical filaments (PHF) which are found in NFT and degenerative neurites of senile plaques
  • This ability of GSK-3β to convert tau proteins to PHF has been demonstrated in vitro using primary cultures of embryonic rat hippocampal neurons
  • Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

Compare Similar Items

Show Difference

Img

Fischer Scientific

BDB610202

--


Antigen:
GSK-3β

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Rat GSK-3β aa. 1-160

Quantity:
150 μg

Research Discipline:
Cell Biology

Target Species:
Canine, Chicken, Human, Mouse, Rat

Isotype:
IgG1

Applications:
Western Blot

Clone:
7

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

Img

Fischer Scientific

BDB610203

--


Antigen:
Cox-2

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Quantity:
50 μg

Research Discipline:
Cell Biology

Target Species:
Chicken, Human, Mouse

Isotype:
IgG1

Applications:
Western Blot

Clone:
33

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

Img

Fischer Scientific

BDB610204

--


Antigen:
Cox-2

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Quantity:
150 μg

Research Discipline:
Cell Biology

Target Species:
Chicken, Human, Mouse

Isotype:
IgG1

Applications:
Western Blot

Clone:
33

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

Img

Fischer Scientific

BDB610207

--


Antigen:
PKCλ

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Human PKCγ aa. 397-558

Quantity:
50 μg

Research Discipline:
Cell Biology

Target Species:
Canine, Chicken, Human, Mouse, Rat

Isotype:
IgG1

Applications:
Western Blot

Clone:
41

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.