BDB610036

Crk Mouse, Unlabeled, Clone: 22, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB610036-Each-of-1 In Stock ₹ 47,571.36

BDB610036 - Each of 1

₹ 47,571.36

In Stock

Quantity

1

Base Price: ₹ 47,571.36

GST (18%): ₹ 8,562.845

Total Price: ₹ 56,134.205

Antigen

Crk

Classification

Monoclonal

Concentration

250μg/mL

Formulation

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen

Human Crk aa. 102 to 304

Quantity

150 μg

Research Discipline

Cell Biology

Target Species

Bovine, Canine, Chicken, Frog, Human, Mouse, Rat

Isotype

IgG2a

Applications

Western Blot

Clone

22

Conjugate

Unconjugated

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

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Description

  • Crk was first isolated as the v- crk oncogene from chicken retroviruses CT10 and ASV-1
  • All human cell lines examined to date express a 40 kDa Crk protein
  • In addition, there is variable expression of 42 kDa and 28 kDa Crk proteins
  • The c- crk gene is one of a class of genes, such as Nck and GRB2/ASH , which encode proteins that consist mainly of SH2 and SH3 domains
  • These proteins function as adaptor molecules in tyrosine kinase signal transduction pathways
  • The SH2 domains interact with phosphotyrosine-containing peptides, while the SH3 domains can enhance this interaction and/or bind to other cellular components
  • Both the SH2 and SH3 domains of the human Crk protein are required for differentiation of PC12 cells
  • Thus, Crk has a role in an NGF-induced signaling pathway that involves activation of p21ras
  • Furthermore, three proteins of 118 kDa, 125 kDa, and 136 kDa which specifically bind to the Crk SH3 domain have been identified.

Compare Similar Items

Show Difference

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Fischer Scientific

BDB610036

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Antigen:
Crk

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Human Crk aa. 102 to 304

Quantity:
150 μg

Research Discipline:
Cell Biology

Target Species:
Bovine, Canine, Chicken, Frog, Human, Mouse, Rat

Isotype:
IgG2a

Applications:
Western Blot

Clone:
22

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

Img

Fischer Scientific

BDB610037

--


Antigen:
Cdk1

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Human p34 [cdc2] aa. 283 to 297

Quantity:
50 μg

Research Discipline:
Cell Biology

Target Species:
Human, Mouse, Rat

Isotype:
IgG1

Applications:
Western Blot

Clone:
1

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Fischer Scientific

BDB610038

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Antigen:
Cdk1

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Human p34 [cdc2] aa. 283 to 297

Quantity:
150 μg

Research Discipline:
Cell Biology

Target Species:
Human, Mouse, Rat

Isotype:
IgG1

Applications:
Western Blot

Clone:
1

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Antigen:
Ras-GAP

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Human Ras-GAP aa.381 to 390

Quantity:
50 μg

Research Discipline:
Cell Biology

Target Species:
Canine, Chicken, Frog, Human, Mouse, Rat

Isotype:
IgG1

Applications:
Western Blot

Clone:
13

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.