BDB610121

MEK1 Mouse, Unlabeled, Clone: 25/MEK1, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB610121-Each-of-1 In Stock ₹ 23,956.80

BDB610121 - Each of 1

₹ 23,956.80

In Stock

Quantity

1

Base Price: ₹ 23,956.80

GST (18%): ₹ 4,312.224

Total Price: ₹ 28,269.024

Antigen

MEK1

Classification

Monoclonal

Concentration

250μg/mL

Formulation

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen

Human MEK1 aa. 2-124

Quantity

50 μg

Research Discipline

Cell Biology

Target Species

Canine, Chicken, Frog, Human, Mouse, Rat

Isotype

IgG2a

Applications

Western Blot

Clone

25/MEK1

Conjugate

Unconjugated

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

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Description

  • MEK1 (MapK/ERK Kinase 1) is a 45kDa member of the MEK family of dual specificity kinases
  • MEK is activated by a variety of cellular serine/threonine kinases including c-Raf, A-Raf, c-mos, and MEK Kinase-1
  • Activated MEK phosphorylates MAP kinase (ERK) at threonine and tyrosine residues
  • This results in activation of ERK and its signaling pathway
  • MEK is highly specific for ERK and various MEKs preferentially phosphorylate individual ERK isoforms
  • MEK1 only activates ERK1 and ERK2
  • This specificity may result from variations in ERK regions that are known as the phosphorylation lip and kinase backbone
  • MEK's localization is cytoplasmic, but mitogenic stimulation induces a mass translocation to the nucleus
  • Mechanisms behind this nuclear translocation remain unknown
  • However, MEK contains an N-terminal nuclear export signal (NES) that mediates its rapid exodus from the nucleus and restores its unstimulated cellular distribution
  • Host Species: Mouse Clone: 25 Isotype: IgG2a Species Reactivity: Human Immunogen: Human MEK1 aa
  • 2-124 Formula Weight [Chemical]: 45kDa Bioimaging, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

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Fischer Scientific

BDB610121

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Antigen:
MEK1

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Human MEK1 aa. 2-124

Quantity:
50 μg

Research Discipline:
Cell Biology

Target Species:
Canine, Chicken, Frog, Human, Mouse, Rat

Isotype:
IgG2a

Applications:
Western Blot

Clone:
25/MEK1

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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BDB610122

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Antigen:
MEK1

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Human MEK1 aa. 2-124

Quantity:
150 μg

Research Discipline:
Cell Biology

Target Species:
Canine, Chicken, Frog, Human, Mouse, Rat

Isotype:
IgG2a

Applications:
Western Blot

Clone:
25/MEK1

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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BDB610123

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Antigen:
ERK (pan ERK)

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Rat ERK2 aa. 219-358

Quantity:
50 μg

Research Discipline:
Cell Biology

Target Species:
Canine, Chicken, Frog, Human, Mouse, Rat

Isotype:
IgG2a

Applications:
Western Blot

Clone:
16

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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BDB610124

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Antigen:
ERK (pan ERK)

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Rat ERK2 aa. 219-358

Quantity:
150 μg

Research Discipline:
Cell Biology

Target Species:
Canine, Chicken, Frog, Human, Mouse, Rat

Isotype:
IgG2a

Applications:
Western Blot

Clone:
16

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.