BDB610045
PI3-Kinase Mouse, Unlabeled, Clone: 4, BD
Manufacturer: Fischer Scientific
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Antigen
PI3-Kinase
Classification
Monoclonal
Concentration
250μg/mL
Formulation
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen
Human PI3-Kinase α subunit aa. 562 to 724
Quantity
50 μg
Research Discipline
Cell Biology
Target Species
Canine, Chicken, Human, Mouse, Rat
Isotype
IgG2a
Applications
Western Blot
Clone
4
Conjugate
Unconjugated
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at -20°C.
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Description
- PI3-kinase phosphorylates the D-3 position of the inositol ring of phosphatidylinositol (PtdIns), PtdIns(4)P and PtdIns(4,5)P2 to produce the respective PI3-phosphorylated derivatives
- PI3-kinase exists as a heterodimer of 85 kDa (p85) and 110 kDa (p110) subunits
- The p85 subunit contains two SH2 domains and an SH3 domain
- It associates with and serves as a substrate for activated growth factor receptor tyrosine kinases
- p85 may serve as regulator of the catalytic subunit, p110, by acting as the link between PI3-kinase and the ligand-activated receptor
- Two distinct forms of the p85 subunit have been described: 1) p85 α; , which binds tightly to the catalytic subunit, and 2) p85ß, a protein whose function is presently unknown
- Both isoforms bind to activated receptors and serve as tyrosine kinase substrates.
Compare Similar Items
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Antigen: PI3-Kinase
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Human PI3-Kinase α subunit aa. 562 to 724
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Canine, Chicken, Human, Mouse, Rat
Isotype: IgG2a
Applications: Western Blot
Clone: 4
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
PI3-Kinase
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Human PI3-Kinase α subunit aa. 562 to 724
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Canine, Chicken, Human, Mouse, Rat
Isotype:
IgG2a
Applications:
Western Blot
Clone:
4
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: PI3-Kinase
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Human PI3-Kinase α subunit aa. 562 to 724
Quantity: 150 μg
Research Discipline: Cell Biology
Target Species: Canine, Chicken, Human, Mouse, Rat
Isotype: IgG2a
Applications: Western Blot
Clone: 4
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
PI3-Kinase
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Human PI3-Kinase α subunit aa. 562 to 724
Quantity:
150 μg
Research Discipline:
Cell Biology
Target Species:
Canine, Chicken, Human, Mouse, Rat
Isotype:
IgG2a
Applications:
Western Blot
Clone:
4
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: Paxillin
Classification: Monoclonal
Concentration: 1.0mg/mL
Formulation: Aqueous buffered solution containing glycerol and ≤0.09% sodium azide.
Immunogen: Chicken Paxillin aa. 1 to 557
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Canine, Chicken, Human, Mouse, Rat
Isotype: IgG1
Applications: Western Blot
Clone: 349
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
Paxillin
Classification:
Monoclonal
Concentration:
1.0mg/mL
Formulation:
Aqueous buffered solution containing glycerol and ≤0.09% sodium azide.
Immunogen:
Chicken Paxillin aa. 1 to 557
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Canine, Chicken, Human, Mouse, Rat
Isotype:
IgG1
Applications:
Western Blot
Clone:
349
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: Paxillin
Classification: Monoclonal
Concentration: 1.0mg/mL
Formulation: Aqueous buffered solution containing glycerol and ≤0.09% sodium azide.
Immunogen: Chicken Paxillin aa. 1 to 557
Quantity: 150 μg
Research Discipline: Cell Biology
Target Species: Canine, Chicken, Human, Mouse, Rat
Isotype: IgG1
Applications: Western Blot
Clone: 349
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
Paxillin
Classification:
Monoclonal
Concentration:
1.0mg/mL
Formulation:
Aqueous buffered solution containing glycerol and ≤0.09% sodium azide.
Immunogen:
Chicken Paxillin aa. 1 to 557
Quantity:
150 μg
Research Discipline:
Cell Biology
Target Species:
Canine, Chicken, Human, Mouse, Rat
Isotype:
IgG1
Applications:
Western Blot
Clone:
349
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.