BDB610966
ZO-1 Mouse anti-Human, Unlabeled, Clone: 1, BD
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB610966-Each-of-1 | In Stock | ₹ 24,470.16 |
BDB610966 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 24,470.16
GST (18%): ₹ 4,404.629
Total Price: ₹ 28,874.789
Antigen
ZO-1
Classification
Monoclonal
Concentration
250μg/mL
Formulation
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen
Human ZO-1 aa. 1048-1247
Quantity
50 μg
Research Discipline
Cell Biology
Target Species
Human
Isotype
IgG1
Applications
Western Blot
Clone
1
Conjugate
Unconjugated
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at -20°C.
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Description
- Tight junctions ( z onulae o ccludens) are critical to the maintenance of cell polarity and intracellular barriers between epithelial and endothelial cells
- Protein components of the tight junctions include actin filaments, symplekin, occludin, Rab3B, AF-6, 7H6, ZO-1, and ZO-2
- Analysis of ZO-1 and -2 resulted in their inclusion in the MAGUK protein family
- This family also includes the discs large tumor suppressor protein (Dlg-A) of Drosophila ; p55, an erythrocyte membrane protein; and PSD-95/SAP90, a synaptic membrane protein
- All family members contain a region homologous to guanylate kinase (GuK), a src homology (SH3) domain, and multiple PDZ domains
- Through these elements, MAGUK proteins function in signal transduction and, possibly, tumor suppression
- ZO-1 is a peripheral membrane phosphoprotein that binds to other tight junction proteins such as occludin and AF-6
- Via its SH3 domain, ZO-1 interacts with a serine protein kinase that phosphorylates a region immediately C-terminal of the SH3 domain
- Taken together, these data indicate that ZO-1 is a critical element in the formation of tight junctions and may also serve an important role in signaling and tumor suppression.
Compare Similar Items
Show Difference
Antigen: ZO-1
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Human ZO-1 aa. 1048-1247
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG1
Applications: Western Blot
Clone: 1
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
ZO-1
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Human ZO-1 aa. 1048-1247
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG1
Applications:
Western Blot
Clone:
1
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: ZO-1
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Human ZO-1 aa. 1048-1247
Quantity: 150 μg
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG1
Applications: Western Blot
Clone: 1
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
ZO-1
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Human ZO-1 aa. 1048-1247
Quantity:
150 μg
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG1
Applications:
Western Blot
Clone:
1
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: Ki-67
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Human Ki-67 aa. 1547-1742
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG1
Applications: Western Blot
Clone: 35
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
Ki-67
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Human Ki-67 aa. 1547-1742
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG1
Applications:
Western Blot
Clone:
35
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: Ki-67
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Human Ki-67 aa. 1547-1742
Quantity: 150 μg
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG1
Applications: Western Blot
Clone: 35
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
Ki-67
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Human Ki-67 aa. 1547-1742
Quantity:
150 μg
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG1
Applications:
Western Blot
Clone:
35
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.