BDB611165

Hic5 Mouse, Unlabeled, Clone: 34, BD

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 BDB611165-Each-of-1 In Stock ₹ 48,640.86

BDB611165 - Each of 1

₹ 48,640.86

In Stock

Quantity

1

Base Price: ₹ 48,640.86

GST (18%): ₹ 8,755.355

Total Price: ₹ 57,396.215

Antigen

Hic5

Classification

Monoclonal

Concentration

250μg/mL

Formulation

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen

Mouse Hic-5 aa. 73-186

Quantity

150 μg

Research Discipline

Cell Biology

Target Species

Canine, Human, Mouse, Rat

Isotype

IgG1

Applications

Western Blot

Clone

34

Conjugate

Unconjugated

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

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Description

  • Focal adhesions are cell structures terminal to the actin-stress fiber bundles
  • They attach cultured cells to their substratum or extracellular matrix
  • These adhesions occur through the integrin receptor molecules which link cytoskeletal proteins and extracellular matrix
  • The intracellular adhesion is composed of a number of proteins such as paxillin, VASP, vinculin, and the focal-adhesion kinases FAK and PYK2/CAKβ
  • Hic-5, also described as hydrogen peroxide inducible-mRNA, is a focal adhesion protein that binds to FAK and PYK2
  • It is ubiquitously expressed with the highest levels found in lung, spleen, and heart
  • Induction of Hic-5 is accomplished by hydrogen peroxide or TGFβ1 and is repressed in K-ras transformed cells
  • Like paxillin, Hic-5 is tyrosine phosphorylated in Src-transformed cells and is highly similar to paxillin in its primary structure
  • Both proteins contain LIM domains and LD motifs
  • In addition, Hic-5 localizes to focal adhesions and co-immunoprecipitates with PYK2/CAKβ in vivo
  • Thus, Hic-5 may be a substrate for CAKβ and play a role in signal transduction during proliferation, cell motility, and adhesion
  • Host Species: Mouse Clone: 34 Isotype: IgG1 Species Reactivity: Rat Immunogen: Mouse Hic-5 aa
  • 73-186 Formula Weight [Chemical]: 50kDa Immunofluorescence, Western Blotting

Compare Similar Items

Show Difference

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Fischer Scientific

BDB611165

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Antigen:
Hic5

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Mouse Hic-5 aa. 73-186

Quantity:
150 μg

Research Discipline:
Cell Biology

Target Species:
Canine, Human, Mouse, Rat

Isotype:
IgG1

Applications:
Western Blot

Clone:
34

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Antigen:
SATB1

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Human SATB1 aa. 550-667

Quantity:
50 μg

Research Discipline:
Cell Biology

Target Species:
Human, Mouse, Rat

Isotype:
IgG1

Applications:
Western Blot

Clone:
14

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Antigen:
GS28

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Rat GS28 aa. 3-108

Quantity:
50 μg

Research Discipline:
Cell Biology

Target Species:
Human, Mouse, Rat

Isotype:
IgG2a

Applications:
Western Blot

Clone:
1

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Antigen:
BRUCE

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Mouse BRUCE aa. 372-571

Quantity:
150 μg

Research Discipline:
Cell Biology

Target Species:
Canine, Human, Mouse, Rat

Isotype:
IgG1

Applications:
Western Blot

Clone:
4

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.