BDB740023

CD22.2 Mouse anti-Mouse, Brilliant Violet 421, Clone: Cy34.1, BD Optibuild™

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB740023-Each-of-1 In Stock ₹ 34,224.00

BDB740023 - Each of 1

₹ 34,224.00

In Stock

Quantity

1

Base Price: ₹ 34,224.00

GST (18%): ₹ 6,160.32

Total Price: ₹ 40,384.32

Antigen

CD22.2

Classification

Monoclonal

Concentration

0.2mg/mL

Description

Lyb8.2; Lyb-8.2; BL-CAM; Siglec-2

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

Cy34.1

Conjugate

Brilliant Violet 421

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

B10.D2 mouse splenocytes

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The Cy34.1 monoclonal antibody specifically binds to the B-lymphocyte differentiation antigen CD22 on strains having the Lyb-8.2 alloantigen ( e.g ., A, BALB/c, CBA, C3H/He, C57BL, C57L, C58, SJL, SWR, but not AKR, DBA/1, DBA/2, NZB, PL)
  • CD22 is expressed at high levels on mature peripheral B lymphocytes (follicular and marginal zone), B-1 cells (CD5+ B cells), and plasma cells
  • It is a member of the Ig gene superfamily and associates with the B-cell antigen receptor
  • Its sialic acid- binding immunoglobulin-like lectin (siglec) extracellular region mediates B-cell adhesion to ligands on endothelial cells in the bone marrow
  • Its intracellular domain is phosphorylated after cross-linking of antigen receptor or MHC class II antigen
  • It is involved in negative regulation of B-cell activation and protection from autoimmunity
  • B-cell proliferative responses to LPS or anti-mouse Ig µ chain are augmented in the presence of Cy34.1 mAb
  • The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50-nm filter)
  • BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates.

Compare Similar Items

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BD Biosciences

BDB740023

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Antigen:
CD22.2

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Lyb8.2; Lyb-8.2; BL-CAM; Siglec-2

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
Cy34.1

Conjugate:
Brilliant Violet 421

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
B10.D2 mouse splenocytes

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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BD Biosciences

BDB740024

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Antigen:
CD4

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Cd4; CD4 antigen; L3T4; Ly-4; T-cell surface antigen T4/Leu-3

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
H129.19

Conjugate:
Brilliant Violet 421

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
A.TH mouse CTL clone A15.1.17

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
CD14

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Cd14; CD14 antigen; Myeloid cell-specific leucine-rich glycoprotein

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
rmC5-3

Conjugate:
Brilliant Violet 421

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Recombinant Mouse CD14

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
CD62E

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Sele; E-selectin; Elam; ELAM-1; LECAM2; LYAM2

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
10E9.6

Conjugate:
Brilliant Violet 421

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Mouse brain capillary endothelioma bEnd.3 (TNFα-stimulated)

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.