BDB740327

CD325 Mouse anti-Human, BUV395, Clone: 8C11, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB740327-Each-of-1 In Stock ₹ 47,400.24

BDB740327 - Each of 1

₹ 47,400.24

In Stock

Quantity

1

Base Price: ₹ 47,400.24

GST (18%): ₹ 8,532.043

Total Price: ₹ 55,932.283

Antigen

CD325

Classification

Monoclonal

Concentration

0.2mg/mL

Description

Cadherin-2, N-Cadherin; NCAD; CDHM; CDH2

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

8C11

Conjugate

Brilliant Ultraviolet 395

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Human extracellular N-Cadherin domain Recombinant Protein

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The 8C11 monoclonal antibody recognizes the extracellular domain of human N-Cadherin (CD325)
  • Cadherins are a family of Ca2+ -dependent intercellular adhesion molecules that play a central role in controlling morphogenetic movements during d evelopment
  • Their function is regulated by association with the actin cytoskeleton by a complex of cytoplasmic proteins called the catenins (α, β, γ)
  • Members of the cadherin family include P-cadherin , E-cadherin (uvomorulin), N-cadherin (neural cadherin) , R-cadherin, cadherin 5, L-CAM, and EP-cadherin
  • N-cadherin mRNA is found at elevated levels in brain and heart and at a much lower level in liver
  • Mechanisms such as mRNA expression, cytokine modulation, and protease-mediated turnover modulate N-cadherin protein levels during development
  • In addition, N-cadherin function is indirectly regulated by endogenous kinases and phosphatases
  • Tyrosine phosphorylation of β-catenin complexed with N-cadherin results in dissociation of N-cadherin from actin
  • However, N-cadherin also interacts with a PTP1B-like phosphatase that dephosphorylates β-catenin and promotes N-cadherin/actin association
  • Thus, N-cadherin is an integral adhesion molecule whose function is regulated by protein-protein interactions and phosphoryla tion/dephosphorylation events
  • The antibody was conjugated to BD Horizon™ BUV395 which is part of the BD Horizon Brilliant™ Ultraviolet family of dyes
  • This dye has been exclusively developed by BD Biosciences to have minimal spillover into other detectors, making it an optimal choice for multicolor flow cytometry
  • With an Ex Max at 348nm and an Em Max at 395nm, BD Horizon BUV395 can be excited with a 355nm laser and detected with a 379/28 filter.

Compare Similar Items

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BD Biosciences

BDB740327

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Antigen:
CD325

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Cadherin-2, N-Cadherin; NCAD; CDHM; CDH2

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
8C11

Conjugate:
Brilliant Ultraviolet 395

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Human extracellular N-Cadherin domain Recombinant Protein

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

BD Biosciences

BDB740329

--


Antigen:
CD54

Classification:
Monoclonal

Concentration:
__

Description:
__

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
LB-2

Conjugate:
Brilliant Ultraviolet 395

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Major histocompatibility Class II antigen negative variant of human B-lymphoblastoid cell line

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with BD Horizon BUV395 under optimal conditions that minimize unconjugated dye and antibody.

Img

BD Biosciences

BDB740330

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Antigen:
CD146

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
S-endo 1; S-endo; Muc18; Mcam; Gicerin

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
ME-9F1

Conjugate:
Brilliant Ultraviolet 395

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
CBA/J Mouse lymph node Cell Line

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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BD Biosciences

BDB740331

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Antigen:
CD276

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Cd276; B7-H3; B7 homolog 3; B7h3; B7RP-2; Costimulatory molecule

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
MIH32

Conjugate:
Brilliant Ultraviolet 395

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Mouse B7-H3 Transfected Cell Line

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.