BDB740530

CD3 molecular complex Rat anti-Mouse, Brilliant Violet 650, Clone: 17A2, BD Optibuild™

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB740530-Each-of-1 In Stock ₹ 34,224.00

BDB740530 - Each of 1

₹ 34,224.00

In Stock

Quantity

1

Base Price: ₹ 34,224.00

GST (18%): ₹ 6,160.32

Total Price: ₹ 40,384.32

Antigen

CD3 molecular complex

Classification

Monoclonal

Concentration

0.2mg/mL

Description

CD3; CD3 epsilon; Cd3e; CD3ε; T3e

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG2b κ

Applications

Flow Cytometry

Clone

17A2

Conjugate

Brilliant Violet 650

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

γδ TCR-positive T-T hybridoma D1

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The 17A2 monoclonal antibody specifically binds to the T-cell receptor-associated CD3 complex that is expressed on many thymocytes and mature T lymphocytes
  • Plate-bound 17A2 antibody has been reported to induce IL-2 production by cultured T cells in the absence of accessory cells
  • The binding of the 17A2 antibody to T cells can be blocked by the anti-CD3e mAb 145-2C11 (Cat
  • No
  • 557306/553058/550275)
  • This suggests that the 17A2 antibody recognizes an epitope of the CD3 epsilon chain
  • In vivo treatment with 17A2 antibody has been reported to partially deplete T lymphocytes and temporarily down-modulates CD3 expression on T cells
  • The antibody was conjugated to BD Horizon™ BV650 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 650-nm
  • BD Horizon BV650 can be excited by the violet laser and detected in a filter used to detect APC-like dyes (eg, 660/20-nm filter)
  • Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors
  • However, the spillover can be corrected through compensation as with any other dye combination.

Compare Similar Items

Show Difference

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BD Biosciences

BDB740530

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Antigen:
CD3 molecular complex

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
CD3; CD3 epsilon; Cd3e; CD3ε; T3e

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
17A2

Conjugate:
Brilliant Violet 650

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
γδ TCR-positive T-T hybridoma D1

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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BD Biosciences

BDB740531

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Antigen:
CD140a

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Pdgfra; Pdgfr2; PDGF-R alpha; Platelet derived growth factor receptor alpha

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
APA5

Conjugate:
Brilliant Violet 650

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Mouse PDGF Receptor α chain

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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BDB740532

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Antigen:
CD70

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
CD27 ligand; CD27l, CD27LG; Tnfsf7; Ki-24 Antigen

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
FR70

Conjugate:
Brilliant Violet 650

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
BALB/c mouse B lymphoma A20.2J

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
CD144

Classification:
Monoclonal

Concentration:
__

Description:
__

Host Species:
Rat

Purification Method:
__

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
11D4.1

Conjugate:
Brilliant Violet 650

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Mouse VE-Cadherin-Ig Fusion

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with BD Horizon BV650 under optimal conditions that minimize unconjugated dye and antibody.