BDB742391

CD8b Mouse anti-Human, Brilliant Violet 510, Clone: 2ST8.5H7, BD Optibuild™

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB742391-Each-of-1 In Stock ₹ 47,400.24

BDB742391 - Each of 1

₹ 47,400.24

In Stock

Quantity

1

Base Price: ₹ 47,400.24

GST (18%): ₹ 8,532.043

Total Price: ₹ 55,932.283

Antigen

CD8b

Clone

2ST8.5H7

Conjugate

Brilliant Violet 510

Gene Alias

CD8B, CD8B1, CD8 beta, CD8β, Leu2, Ly3, LYT3

Immunogen

CD8+ suppressor T-cell

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG2a κ

Description

  • The 2ST8.5H7 monoclonal antibody specifically recognizes an epitope formed by the combination of CD8 alpha and beta chains
  • The majority of peripheral blood CD8+ T lymphocytes expresses a CD8 cells and CD8+ CD8 s
  • The 2ST8.5H7 antibody can therefore be used to selectively bind to CD8+ T cells while excluding CD8+ NK cells
  • CD8 binds to class I major histocompatibility (MHC) molecules, resulting in increased adhesion between the CD8+ T lymphocytes and target cells
  • Binding of CD8 to class I MHC molecules enhances the activation of resting T lymphocytes
  • CD8 is coupled to a protein tyrosine kinase, p56lck
  • The CD8:p56lck complex can play a role in T-lymphocyte activation through mediation of the interactions between CD8 and the CD3/TCR complex
  • The antibody was conjugated to BD Horizon™ BV510 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • With an Ex Max of 405nm and Em Max at 510nm, BD Horizon BV510 can be excited by the violet laser and detected in the BD Horizon V500 (525/50nm) filter set
  • BD Horizon BV510 conjugates are useful for the detection of dim markers off the violet laser
  • BV510 is a polymer-based dye that is brighter than BD Horizon V500
  • Due to similar excitation and emission properties, BD Horizon BV510 and BD Horizon V500 cannot be used simultaneously.

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BD Biosciences

BDB742391

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Antigen:
CD8b

Clone:
2ST8.5H7

Conjugate:
Brilliant Violet 510

Gene Alias:
CD8B, CD8B1, CD8 beta, CD8β, Leu2, Ly3, LYT3

Immunogen:
CD8+ suppressor T-cell

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2a κ

Img

BD Biosciences

BDB742393

--


Antigen:
CD8b

Clone:
2ST8.5H7

Conjugate:
Brilliant Violet 650

Gene Alias:
CD8B, CD8B1, CD8 beta, CD8β, Leu2, Ly3, LYT3

Immunogen:
CD8+ suppressor T-cell

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2a κ

Img

BD Biosciences

BDB742397

--


Antigen:
CD37

Clone:
M-B371

Conjugate:
Brilliant Violet 421

Gene Alias:
GP52-40, Tetraspanin-26, TSPAN26, Tspan-26

Immunogen:
__

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Img

BD Biosciences

BDB742399

--


Antigen:
CD37

Clone:
M-B371

Conjugate:
Brilliant Violet 605

Gene Alias:
GP52-40, Tetraspanin-26, TSPAN26, Tspan-26

Immunogen:
__

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ