BDB742570

CD105 Mouse anti-Human, Brilliant Violet 711, Clone: 266, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB742570-Each-of-1 In Stock ₹ 47,614.14

BDB742570 - Each of 1

₹ 47,614.14

In Stock

Quantity

1

Base Price: ₹ 47,614.14

GST (18%): ₹ 8,570.545

Total Price: ₹ 56,184.685

Antigen

CD105

Clone

266

Conjugate

Brilliant Violet 711

Gene Alias

Endoglin, ENG, END, HHT1, ORW, ORW1

Immunogen

Human Umbilical Vein Endothelial Cells

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

Description

  • The 266 monoclonal antibody specifically binds to CD105
  • CD105 presents an integral membrane homodimer protein with subunits of 95 kDa found on vascular endothelial cells and syncytiotrophoblasts of placenta
  • CD105 is weakly expressed on stromal fibroblasts
  • It is also expressed on U937 cells, activated macrophages, and mesenchymal stem cells
  • CD105 is a component of the TGF-βreceptor system in human umbilical vein endothelial cells and binds TGF-β1 and TGF-β3 with high affinity but does not bind toTGF-β2
  • Expression of CD105 is increased on activated endothelium in tissues undergoing angiogenesis, such as in tumors, or in cases of wound healing or dermal inflammation
  • The antibody was conjugated to BD Horizon™ BV711 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 711nm
  • BD Horizon BV711 can be excited by the violet laser and detected in a filter used to detect Cy™5.5 / Alexa Fluor™ 700-like dyes (eg, 712/20nm filter)
  • Due to the excitation and emission characteristics of the acceptor dye, there may be moderate spillover into the Alexa Fluor™ 700 and PerCP-Cy5.5 detectors
  • However, the spillover can be corrected through compensation as with any other dye combination
  • BV711 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 711 nm
  • This dye offers a very bright choice for the violet laser
  • Due to the excitation and emission characteristics of the acceptor dye, there may be moderate spillover into the Alexa Fluor™ 700 and PerCP-Cy5.5 detectors
  • BV711 will also have moderate spillover into the BD Horizon Brilliant™ Violet 786 detector.

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BD Biosciences

BDB742570

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Antigen:
CD105

Clone:
266

Conjugate:
Brilliant Violet 711

Gene Alias:
Endoglin, ENG, END, HHT1, ORW, ORW1

Immunogen:
Human Umbilical Vein Endothelial Cells

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Img

BD Biosciences

BDB742573

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Antigen:
CD132

Clone:
AG184

Conjugate:
Brilliant Violet 650

Gene Alias:
IL2RG, IL-2RG, IL-2Rγ, Common gamma chain, γc, CIDX, SCIDX, SCIDX1, IMD4

Immunogen:
__

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Img

BD Biosciences

BDB742579

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Antigen:
GITR Ligand

Clone:
MIH44

Conjugate:
Brilliant Violet 711

Gene Alias:
Tnfsf18, Gitrl,Glucocorticoid-induced-tumor necrosis factor receptor ligand

Immunogen:
GITRL/GFP-transfected L cells

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2b κ

Img

BD Biosciences

BDB742580

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Antigen:
GITR Ligand

Clone:
MIH44

Conjugate:
Brilliant Violet 786

Gene Alias:
Tnfsf18, Gitrl,Glucocorticoid-induced-tumor necrosis factor receptor ligand

Immunogen:
GITRL/GFP-transfected L cells

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2b κ