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BDB742641

CD11b Mouse anti-Human, Brilliant Violet 711, Clone: D12, BD Optibuild™

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB742641-Each-of-1 In Stock ₹ 47,614.14

BDB742641 - Each of 1

₹ 47,614.14

In Stock

Quantity

1

Base Price: ₹ 47,614.14

GST (18%): ₹ 8,570.545

Total Price: ₹ 56,184.685

Antigen

CD11b

Clone

D12

Conjugate

Brilliant Violet 711

Gene Alias

MAC-1A, Mac-1, ITGAM, Integrin alpha M, CR3A, CR-3 alpha, Mo1, SLEB6

Immunogen

Human peripheral blood T lymphocytes

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG2a κ

Description

  • The D12 monoclonal antibody specifically binds to CD11b which is also known as Integrin alpha M (IntegrinαM), Mac-1 subunit alpha (Mac-1a) or complement receptor 3 alpha chain (CR3a)
  • CD11b is encoded by ITGAM /(integrin subunit alpha M) and belongs to the integrin alpha subunit gene family
  • CD11b is expressed as a ñ165-kDa type I transmembrane glycoprotein that associates with the ñ95-kDa integrin β2(CD18) to form the heterodimeric CD11b/CD18 (αM/β2) complex which also known as Mac-1 or CR3
  • CD11b is expressed on monocytes, dendritic cells, granulocytes, as well as on some T cells, B cells, and NK cells
  • CD11b functions in cell-cell and cell-substrate interactions and is a receptor for multiple ligands including inactivated C3b (iC3b), ICAM-1 (CD54), ICAM-2 (CD102), ICAM-3 (CD50) or fibrinogen
  • Mac-1 regulates leucocyte adhesion and migration, as well as phagocytosis of opsonized particles
  • The antibody was conjugated to BD Horizon™ BV711 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 711nm
  • BD Horizon BV711 can be excited by the violet laser and detected in a filter used to detect Cy™5.5 / Alexa Fluor™ 700-like dyes (eg, 712/20nm filter)
  • Due to the excitation and emission characteristics of the acceptor dye, there may be moderate spillover into the Alexa Fluor™ 700 and PerCP-Cy5.5 detectors
  • However, the spillover can be corrected through compensation as with any other dye combination
  • BV711 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 711 nm
  • This dye offers a very bright choice for the violet laser
  • Due to the excitation and emission characteristics of the acceptor dye, there may be moderate spillover into the Alexa Fluor™ 700 and PerCP-Cy5.5 detectors
  • BV711 will also have moderate spillover into the BD Horizon Brilliant™ Violet 786 detector.

Compare Similar Items

Show Difference

Img

BD Biosciences

BDB742641

--

Antigen:
CD11b
Clone:
D12
Conjugate:
Brilliant Violet 711
Gene Alias:
MAC-1A, Mac-1, ITGAM, Integrin alpha M, CR3A, CR-3 alpha, Mo1, SLEB6
Immunogen:
Human peripheral blood T lymphocytes
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ

Img

BD Biosciences

BDB742642

--

Antigen:
CD11b
Clone:
D12
Conjugate:
Brilliant Violet 786
Gene Alias:
MAC-1A, Mac-1, ITGAM, Integrin alpha M, CR3A, CR-3 alpha, Mo1, SLEB6
Immunogen:
Human peripheral blood T lymphocytes
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ

Img

BD Biosciences

BDB742646

--

Antigen:
CD49b
Clone:
AK-7 (also known as AK7)
Conjugate:
Brilliant Violet 605
Gene Alias:
Integrin alpha-2, ITGA2, VLA-2 alpha, Platelet GPIa, Collagen receptor, BR
Immunogen:
__
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ

Img

BD Biosciences

BDB742647

--

Antigen:
CD49b
Clone:
AK-7 (also known as AK7)
Conjugate:
Brilliant Violet 711
Gene Alias:
Integrin alpha-2, ITGA2, VLA-2 alpha, Platelet GPIa, Collagen receptor, BR
Immunogen:
__
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ