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BDB742647

CD49b Mouse anti-Human, Brilliant Violet 711, Clone: AK-7 (also known as AK7), BD Optibuild™

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB742647-Each-of-1 In Stock ₹ 47,400.24

BDB742647 - Each of 1

₹ 47,400.24

In Stock

Quantity

1

Base Price: ₹ 47,400.24

GST (18%): ₹ 8,532.043

Total Price: ₹ 55,932.283

Antigen

CD49b

Clone

AK-7 (also known as AK7)

Conjugate

Brilliant Violet 711

Gene Alias

Integrin alpha-2, ITGA2, VLA-2 alpha, Platelet GPIa, Collagen receptor, BR

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Description

  • The AK-7 monoclonal antibody specifically binds to CD49b
  • CD49b is also known as integrin α2 chain, VLA-α2, and GP1a
  • CD49b is a type I transmembrane glycoprotein and belongs to the integrin family of extracellular matrix and cell-cell adhesion receptors
  • CD49b is expressed on numerous cell types including platelets, activated T cells, B cells, and monocytes
  • CD49b noncovalently associates with CD29 to form the VLA-2 complex (integrinα2/β1)
  • The VLA-2 complex serves as a receptor for collagen and laminin
  • It can regulate responses mediated by proinflammatory effector cells
  • The antibody was conjugated to BD Horizon™ BV711 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 711nm
  • BD Horizon BV711 can be excited by the violet laser and detected in a filter used to detect Cy™5.5 / Alexa Fluor™ 700-like dyes (eg, 712/20nm filter)
  • Due to the excitation and emission characteristics of the acceptor dye, there may be moderate spillover into the Alexa Fluor™ 700 and PerCP-Cy5.5 detectors
  • However, the spillover can be corrected through compensation as with any other dye combination
  • BV711 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 711 nm
  • This dye offers a very bright choice for the violet laser
  • Due to the excitation and emission characteristics of the acceptor dye, there may be moderate spillover into the Alexa Fluor™ 700 and PerCP-Cy5.5 detectors
  • BV711 will also have moderate spillover into the BD Horizon Brilliant™ Violet 786 detector.

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BDB742647

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Antigen:
CD49b
Clone:
AK-7 (also known as AK7)
Conjugate:
Brilliant Violet 711
Gene Alias:
Integrin alpha-2, ITGA2, VLA-2 alpha, Platelet GPIa, Collagen receptor, BR
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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BD Biosciences

BDB742652

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Antigen:
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Clone:
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Conjugate:
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Gene Alias:
L3T4, T-cell surface antigen T4/Leu-3, W3/25, CD4 antigen (p55)
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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BD Biosciences

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Antigen:
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Clone:
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Conjugate:
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Gene Alias:
L3T4, T-cell surface antigen T4/Leu-3, W3/25, CD4 antigen (p55)
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
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Clone:
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Conjugate:
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Gene Alias:
__
Purification Method:
__
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Classification:
Monoclonal
Concentration:
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Formulation:
__
Host Species:
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Quantity:
50 μg
Primary or Secondary:
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Content And Storage:
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