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BDB742670

CD140a Mouse anti-Human, BUV395, Clone: αR1 (also known as Alpha-R1), BD Optibuild™

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB742670-Each-of-1 In Stock ₹ 47,614.14

BDB742670 - Each of 1

₹ 47,614.14

In Stock

Quantity

1

Base Price: ₹ 47,614.14

GST (18%): ₹ 8,570.545

Total Price: ₹ 56,184.685

Antigen

CD140a

Clone

αR1 (also known as Alpha-R1)

Conjugate

Brilliant Ultraviolet 395

Gene Alias

PDGF Receptor α, PDGFRA, PDGFRα, PDGF-R-alpha, PDGFR2, PGFRA, RHEPDGFRA

Immunogen

Human PDGFRα Transfected Cell Line

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG2a κ

Description

  • The αR1 monoclonal antibody specifically binds to the human platelet derived growth factor (PDGF) receptor α (PDGFRα), also known as CD140a
  • CD140a is a 170 kDa single transmembrane glycoprotein expressed on fibroblasts, smooth muscle cells, glial cells and chondrocytes
  • PDGF receptors α and βare single glycoproteins with intracellular tyrosine kinase domains
  • They are structurally similar to the M-CSF receptor and CD117 (c-kit)
  • Their ligand, PDGF, is a mitogen for connective tissue cells and glial cells
  • PDGF plays a role in wound healing and it also acts as a chemoattractant for fibroblasts, smooth muscle cells, glial cells, monocytes and neutrophils
  • Functional PDGF is secreted in disulfide linked, homodimeric or heterodimeric forms comprised of A or B chains (PDGFAA, PDGF-BB or PDGF-AB)
  • Binding of divalent PDGF induces receptor dimerization with three possible forms: αα, αβ, ββ
  • The PDGFRαsubunit binds both PDGF A and B chains, whereas the PDGFRβ subunit binds only PDGF B chains
  • Although both receptor subunits can stimulate mitogenic responses, only the β subunit can induce chemotaxis.TheαR1antibody is specific for PDGFRαand does not crossreact with PDGFRβ
  • It immunoprecipitates human, monkey, rabbit, pig, dog and cat PDGFRα
  • It does not recognize hamster, rat or mouse PDGFRα
  • The antibody was conjugated to BD Horizon™ BUV395 which is part of the BD Horizon Brilliant™ Ultraviolet family of dyes
  • This dye has been exclusively developed by BD Biosciences to have minimal spillover into other detectors, making it an optimal choice for multicolor flow cytometry
  • With an Ex Max at 348 nm and an Em Max at 395 nm, BD Horizon BUV395 can be excited with a 355 nm laser and detected with a 379/28 filter
  • BUV395 is a UV-excitable dye that has been developed exclusively by BD Biosciences
  • With an excitation max of 348 nm and emission max of 395 nm, BUV395 can be excited by the 355nm laser and detected in a 379/28 filter
  • This dye is optimal for multicolor flow cytometry because it has little to no spillover into other detectors.

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BD Biosciences

BDB742670

--

Antigen:
CD140a
Clone:
αR1 (also known as Alpha-R1)
Conjugate:
Brilliant Ultraviolet 395
Gene Alias:
PDGF Receptor α, PDGFRA, PDGFRα, PDGF-R-alpha, PDGFR2, PGFRA, RHEPDGFRA
Immunogen:
Human PDGFRα Transfected Cell Line
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ

Img

BD Biosciences

BDB742674

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Antigen:
CD238
Clone:
BRIC 203
Conjugate:
Brilliant Violet 711
Gene Alias:
KEL, KELL, Kell blood group, metallo-endopeptidase, ECE3
Immunogen:
Human erythrocytes
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ

Img

BD Biosciences

BDB742675

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Antigen:
CD238
Clone:
BRIC 203
Conjugate:
Brilliant Violet 786
Gene Alias:
KEL, KELL, Kell blood group, metallo-endopeptidase, ECE3
Immunogen:
Human erythrocytes
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ

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BD Biosciences

BDB742680

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Antigen:
CD55
Clone:
IA10
Conjugate:
Brilliant Violet 650
Gene Alias:
DAF; CR; CROM; TC; Complement decay-accelerating factor
Immunogen:
Purified Human Decay Accelerating Factor
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with BD Horizon BV650 under optimal conditions that minimize unconjugated dye and antibody.
Classification:
Monoclonal
Concentration:
__
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ