BDB742675

CD238 Mouse anti-Human, Brilliant Violet 786, Clone: BRIC 203, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB742675-Each-of-1 In Stock ₹ 47,400.24

BDB742675 - Each of 1

₹ 47,400.24

In Stock

Quantity

1

Base Price: ₹ 47,400.24

GST (18%): ₹ 8,532.043

Total Price: ₹ 55,932.283

Antigen

CD238

Clone

BRIC 203

Conjugate

Brilliant Violet 786

Gene Alias

KEL, KELL, Kell blood group, metallo-endopeptidase, ECE3

Immunogen

Human erythrocytes

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

Description

  • The BRIC 203 monoclonal antibody specifically binds to the Kell blood group antigen, Kp(a-b+) but not Kp(a+b-), also known as the Kell blood group metallo-endopeptidase, KELL, ECE3 and CD238
  • CD238 is an approximately 115-kDa type II transmembrane glycoprotein that is encoded by the KEL gene
  • CD238 functions as a zinc endopeptidase that cleaves endothelin-3 into an active form which can function as a vasoconstrictor
  • CD238 is expressed on erythrocytes, human embryonic stem cell-derived endoderm and on cells from various other tissues, including testis, heart, brain and skeletal muscle
  • Decreased expression of CD238 is associated with the McLeod phenotype as a consequence of losing XK protein expression
  • Kell antigen expression can play an important role during blood transfusions and also specific autoimmune diseases related to Kell antigen recognition
  • During development the BRIC 203 monoclonal antibody was found to detect the CD238 antigen by flow cytometric analysis of human erythrocytes
  • It reportedly works in immunoprecipitation and agglutination assays
  • The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 786nm
  • BD Horizon BV786 can be excited by the violet laser and detected in a filter used to detect Cy™7-like dyes (eg, 780/60nm filter)
  • BV786 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 786 nm
  • BV786 offers a bright choice for the 6th detector off the violet laser.

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BD Biosciences

BDB742675

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Antigen:
CD238

Clone:
BRIC 203

Conjugate:
Brilliant Violet 786

Gene Alias:
KEL, KELL, Kell blood group, metallo-endopeptidase, ECE3

Immunogen:
Human erythrocytes

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

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BD Biosciences

BDB742680

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Antigen:
CD55

Clone:
IA10

Conjugate:
Brilliant Violet 650

Gene Alias:
DAF; CR; CROM; TC; Complement decay-accelerating factor

Immunogen:
Purified Human Decay Accelerating Factor

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with BD Horizon BV650 under optimal conditions that minimize unconjugated dye and antibody.

Classification:
Monoclonal

Concentration:
__

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2a κ

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BD Biosciences

BDB742681

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Antigen:
CD55

Clone:
IA10

Conjugate:
Brilliant Violet 786

Gene Alias:
DAF; CR; CROM; TC; Complement decay-accelerating factor

Immunogen:
Purified Human Decay Accelerating Factor

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with BD Horizon BV786 under optimal conditions that minimize unconjugated dye and antibody.

Classification:
Monoclonal

Concentration:
__

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2a κ

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Antigen:
CD66c

Clone:
B6.2/CD66

Conjugate:
Brilliant Violet 421

Gene Alias:
CEACAM6, Carcinoembryonic antigen-related cell adhesion molecule 6, NCA

Immunogen:
Human Breast Carcinoma Extracts

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ