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BDB742719

CD273 Mouse anti-Human, BUV395, Clone: MIH18, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB742719-Each-of-1 In Stock ₹ 47,614.14

BDB742719 - Each of 1

₹ 47,614.14

In Stock

Quantity

1

Base Price: ₹ 47,614.14

GST (18%): ₹ 8,570.545

Total Price: ₹ 56,184.685

Antigen

CD273

Clone

MIH18

Conjugate

Brilliant Ultraviolet 395

Gene Alias

PD-1 ligand 2, PD-L2, B7-DC, PDCD1LG2, PDCD1 ligand 2, PDCD1L2, PDL2, Btdc

Immunogen

Human CD273 Transfected Cell Line

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

Description

  • The MIH18 monoclonal antibody specifically binds to CD273 which is also known as the Programmed Death Ligand 2 (PD-L2) and B7-DC
  • CD273 is a type 1 transmembrane glycoprotein member of the B7 family and Ig superfamily
  • CD273 serves as a ligand for CD279, the Programmed Death 1 (PD-1) receptor
  • CD273 is expressed by dendritic cells, activated monocytes, medullary thymic epithelial cells, placental trophoblasts, and myocardial endothelium
  • CD273 can function as a coinhibitor of T cell functions by acting through CD279
  • Monoclonal antibodies that block the CD273 and CD279 interaction result in enhanced T cell proliferation and cytokine production
  • Thus, CD273 can play an important role in regulating T cell responses
  • Clone MIH18 is reportedly a blocking antibody
  • The antibody was conjugated to BD Horizon™ BUV395 which is part of the BD Horizon Brilliant™ Ultraviolet family of dyes
  • This dye has been exclusively developed by BD Biosciences to have minimal spillover into other detectors, making it an optimal choice for multicolor flow cytometry
  • With an Ex Max at 348 nm and an Em Max at 395 nm, BD Horizon BUV395 can be excited with a 355 nm laser and detected with a 379/28 filter
  • BUV395 is a UV-excitable dye that has been developed exclusively by BD Biosciences
  • With an excitation max of 348 nm and emission max of 395 nm, BUV395 can be excited by the 355nm laser and detected in a 379/28 filter
  • This dye is optimal for multicolor flow cytometry because it has little to no spillover into other detectors.

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BD Biosciences

BDB742719

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Antigen:
CD273
Clone:
MIH18
Conjugate:
Brilliant Ultraviolet 395
Gene Alias:
PD-1 ligand 2, PD-L2, B7-DC, PDCD1LG2, PDCD1 ligand 2, PDCD1L2, PDL2, Btdc
Immunogen:
Human CD273 Transfected Cell Line
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ

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BD Biosciences

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Clone:
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Gene Alias:
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Immunogen:
Mouse
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
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Affinity Purified
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Mouse
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Primary or Secondary:
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Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
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IgG2a κ

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Gene Alias:
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Immunogen:
Mouse
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
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IgG2a κ