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BDB742792

CD156c Mouse anti-Human, Brilliant Violet 786, Clone: 11G2, BD Optibuild™

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB742792-Each-of-1 In Stock ₹ 47,400.24

BDB742792 - Each of 1

₹ 47,400.24

In Stock

Quantity

1

Base Price: ₹ 47,400.24

GST (18%): ₹ 8,532.043

Total Price: ₹ 55,932.283

Antigen

CD156c

Clone

11G2

Conjugate

Brilliant Violet 786

Gene Alias

ADAM 10, AD10, ADA10, MADM, KUZ, Kuzbanian protein homolog, HsT18717, RAK

Immunogen

Human Jurkat Cell Line

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

Description

  • The 11G2 monoclonal antibody specifically binds to CD156c which is also known as Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10)
  • CD156c is a ñ70 kDa type I transmembrane glycoprotein that belongs to the ADAM family
  • It is widely expressed on hematopoietic and non-hematopoietic cells
  • CD156c is expressed on the plasma membrane, as well as by membranes within intracellular compartments and exosomes
  • CD156c serves as a broadly-reactive endopeptidase that cleaves membrane-bound proteins in a process known as ectodomain shedding or release
  • It can cleave transmembrane molecules into soluble forms and thereby regulate the functions of a variety of different receptors and ligands that are involved in cellular signaling and adhesion
  • These include membrane TNF, CX3CL1, CXCL16, Ephrin-A2, Notch and Delta molecules, cadherins, CD23, CD44, IL-6 Receptor/CD126, CD171, and amyloid precursor protein
  • CD156c expression may be constitutive or induced, such as in inflamed tissues, including arthritic joints and in the nervous system
  • Dysregulated CD156c expression may be associated with certain cancers and Alzheimer’s disease
  • The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 786nm
  • BD Horizon BV786 can be excited by the violet laser and detected in a filter used to detect Cy™7-like dyes (eg, 780/60nm filter)
  • BV786 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 786 nm
  • BV786 offers a bright choice for the 6th detector off the violet laser.

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BD Biosciences

BDB742792

--

Antigen:
CD156c
Clone:
11G2
Conjugate:
Brilliant Violet 786
Gene Alias:
ADAM 10, AD10, ADA10, MADM, KUZ, Kuzbanian protein homolog, HsT18717, RAK
Immunogen:
Human Jurkat Cell Line
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ

Img

BD Biosciences

BDB742793

--

Antigen:
CD156c
Clone:
11G2
Conjugate:
Brilliant Ultraviolet 395
Gene Alias:
ADAM 10, AD10, ADA10, MADM, KUZ, Kuzbanian protein homolog, HsT18717, RAK
Immunogen:
Human Jurkat Cell Line
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ

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BD Biosciences

BDB742794

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Antigen:
CD96
Clone:
6F9
Conjugate:
Brilliant Violet 421
Gene Alias:
TACTILE, T cell activation increased late expression
Immunogen:
Human CD96 Transfected Cell Line
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ

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BDB742800

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Antigen:
GARP
Clone:
7B11 (also known as CMSSC-7B11)
Conjugate:
Brilliant Violet 510
Gene Alias:
LRRC32, Garpin, Glycoprotein A repetitions predominant
Immunogen:
Recombinant Human LRRC32
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ