BDB742793
CD156c Mouse anti-Human, BUV395, Clone: 11G2, BD Optibuild™
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB742793-Each-of-1 | In Stock | ₹ 47,614.14 |
BDB742793 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,614.14
GST (18%): ₹ 8,570.545
Total Price: ₹ 56,184.685
Antigen
CD156c
Clone
11G2
Conjugate
Brilliant Ultraviolet 395
Gene Alias
ADAM 10, AD10, ADA10, MADM, KUZ, Kuzbanian protein homolog, HsT18717, RAK
Immunogen
Human Jurkat Cell Line
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification
Monoclonal
Concentration
0.2mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Description
- The 11G2 monoclonal antibody specifically binds to CD156c which is also known as Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10)
- CD156c is a ñ70 kDa type I transmembrane glycoprotein that belongs to the ADAM family
- It is widely expressed on hematopoietic and non-hematopoietic cells
- CD156c is expressed on the plasma membrane, as well as by membranes within intracellular compartments and exosomes
- CD156c serves as a broadly-reactive endopeptidase that cleaves membrane-bound proteins in a process known as ectodomain shedding or release
- It can cleave transmembrane molecules into soluble forms and thereby regulate the functions of a variety of different receptors and ligands that are involved in cellular signaling and adhesion
- These include membrane TNF, CX3CL1, CXCL16, Ephrin-A2, Notch and Delta molecules, cadherins, CD23, CD44, IL-6 Receptor/CD126, CD171, and amyloid precursor protein
- CD156c expression may be constitutive or induced, such as in inflamed tissues, including arthritic joints and in the nervous system
- Dysregulated CD156c expression may be associated with certain cancers and Alzheimer’s disease
- The antibody was conjugated to BD Horizon™ BUV395 which is part of the BD Horizon Brilliant™ Ultraviolet family of dyes
- This dye has been exclusively developed by BD Biosciences to have minimal spillover into other detectors, making it an optimal choice for multicolor flow cytometry
- With an Ex Max at 348 nm and an Em Max at 395 nm, BD Horizon BUV395 can be excited with a 355 nm laser and detected with a 379/28 filter
- BUV395 is a UV-excitable dye that has been developed exclusively by BD Biosciences
- With an excitation max of 348 nm and emission max of 395 nm, BUV395 can be excited by the 355nm laser and detected in a 379/28 filter
- This dye is optimal for multicolor flow cytometry because it has little to no spillover into other detectors.
Compare Similar Items
Show Difference
Antigen: CD156c
Clone: 11G2
Conjugate: Brilliant Ultraviolet 395
Gene Alias: ADAM 10, AD10, ADA10, MADM, KUZ, Kuzbanian protein homolog, HsT18717, RAK
Immunogen: Human Jurkat Cell Line
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD156c
Clone:
11G2
Conjugate:
Brilliant Ultraviolet 395
Gene Alias:
ADAM 10, AD10, ADA10, MADM, KUZ, Kuzbanian protein homolog, HsT18717, RAK
Immunogen:
Human Jurkat Cell Line
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD96
Clone: 6F9
Conjugate: Brilliant Violet 421
Gene Alias: TACTILE, T cell activation increased late expression
Immunogen: Human CD96 Transfected Cell Line
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD96
Clone:
6F9
Conjugate:
Brilliant Violet 421
Gene Alias:
TACTILE, T cell activation increased late expression
Immunogen:
Human CD96 Transfected Cell Line
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: GARP
Clone: 7B11 (also known as CMSSC-7B11)
Conjugate: Brilliant Violet 510
Gene Alias: LRRC32, Garpin, Glycoprotein A repetitions predominant
Immunogen: Recombinant Human LRRC32
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2b κ
Antigen:
GARP
Clone:
7B11 (also known as CMSSC-7B11)
Conjugate:
Brilliant Violet 510
Gene Alias:
LRRC32, Garpin, Glycoprotein A repetitions predominant
Immunogen:
Recombinant Human LRRC32
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ
Antigen: GARP
Clone: 7B11 (also known as CMSSC-7B11)
Conjugate: Brilliant Violet 605
Gene Alias: LRRC32, Garpin, Glycoprotein A repetitions predominant
Immunogen: Recombinant Human LRRC32
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2b κ
Antigen:
GARP
Clone:
7B11 (also known as CMSSC-7B11)
Conjugate:
Brilliant Violet 605
Gene Alias:
LRRC32, Garpin, Glycoprotein A repetitions predominant
Immunogen:
Recombinant Human LRRC32
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ