BDB742832
CD277 Mouse anti-Human, BUV395, Clone: 232-5, BD Optibuild™
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB742832-Each-of-1 | In Stock | ₹ 47,400.24 |
BDB742832 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,400.24
GST (18%): ₹ 8,532.043
Total Price: ₹ 55,932.283
Antigen
CD277
Clone
232-5
Conjugate
Brilliant Ultraviolet 395
Gene Alias
CD277, Butyrophilin 3, BTN3, BTN3A1, BTN3A2, BTN3A3, BTN3.1, BTN3.2, BTN3.3
Immunogen
Human BTN3A3
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification
Monoclonal
Concentration
0.2mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG2a κ
Description
- The 232-5 monoclonal antibody specifically recognizes Butyrophilin 3 (BTN3), which is also known as CD277
- BTN3 is comprised of three structurally related members, BTN3A1, BTN3A2, and BTN3A3
- BTN3 molecules are transmembrane type 1 glycoproteins that belong to the Ig superfamily
- The 232-5 antibody recognizes the variable region of the extracellular domains of BTN3 molecules
- BTN3 molecules are differentially expressed by T, NKT, B, and NK cells, monocytes, macrophages, dendritic cells, as well as some stem cells and tumor cells
- BTN3 expression is decreased upon lymphocyte activation
- The extracellular domain of CD277 is structurally related to the B7 family of proteins that regulate T cell activation
- A soluble form of the 232-5 antibody can serve as an agonist in BTN3-mediated regulation of anti-CD3±anti-CD28 antibody activated CD4+ or CD8+ T cells
- The antibody was conjugated to BD Horizon™ BUV395 which is part of the BD Horizon Brilliant™ Ultraviolet family of dyes
- This dye has been exclusively developed by BD Biosciences to have minimal spillover into other detectors, making it an optimal choice for multicolor flow cytometry
- With an Ex Max at 348 nm and an Em Max at 395 nm, BD Horizon BUV395 can be excited with a 355 nm laser and detected with a 379/28 filter
- BUV395 is a UV-excitable dye that has been developed exclusively by BD Biosciences
- With an excitation max of 348 nm and emission max of 395 nm, BUV395 can be excited by the 355nm laser and detected in a 379/28 filter
- This dye is optimal for multicolor flow cytometry because it has little to no spillover into other detectors.
Compare Similar Items
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Antigen: CD277
Clone: 232-5
Conjugate: Brilliant Ultraviolet 395
Gene Alias: CD277, Butyrophilin 3, BTN3, BTN3A1, BTN3A2, BTN3A3, BTN3.1, BTN3.2, BTN3.3
Immunogen: Human BTN3A3
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2a κ
Antigen:
CD277
Clone:
232-5
Conjugate:
Brilliant Ultraviolet 395
Gene Alias:
CD277, Butyrophilin 3, BTN3, BTN3A1, BTN3A2, BTN3A3, BTN3.1, BTN3.2, BTN3.3
Immunogen:
Human BTN3A3
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ
Antigen: Ig, κ light chain
Clone: 187.1
Conjugate: Brilliant Violet 510
Gene Alias: Ig kappa chain C region, IGKC, Igk-C, Ig, κ
Immunogen: Mouse IgG2b κ secreted by MPC-11 plasmacytoma
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG1 κ
Antigen:
Ig, κ light chain
Clone:
187.1
Conjugate:
Brilliant Violet 510
Gene Alias:
Ig kappa chain C region, IGKC, Igk-C, Ig, κ
Immunogen:
Mouse IgG2b κ secreted by MPC-11 plasmacytoma
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG1 κ
Antigen: Ig, κ light chain
Clone: 187.1
Conjugate: Brilliant Violet 711
Gene Alias: Ig kappa chain C region, IGKC, Igk-C, Ig, κ
Immunogen: Mouse IgG2b κ secreted by MPC-11 plasmacytoma
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG1 κ
Antigen:
Ig, κ light chain
Clone:
187.1
Conjugate:
Brilliant Violet 711
Gene Alias:
Ig kappa chain C region, IGKC, Igk-C, Ig, κ
Immunogen:
Mouse IgG2b κ secreted by MPC-11 plasmacytoma
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG1 κ
Antigen: P-glycoprotein
Clone: 17F9
Conjugate: Brilliant Violet 510
Gene Alias: CD243, ABCB1, ABC20, CLCS, GP170, MDR1, P-GP, PGY1
Immunogen: Human MDR1 Transfected Cell Line
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2b κ
Antigen:
P-glycoprotein
Clone:
17F9
Conjugate:
Brilliant Violet 510
Gene Alias:
CD243, ABCB1, ABC20, CLCS, GP170, MDR1, P-GP, PGY1
Immunogen:
Human MDR1 Transfected Cell Line
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ