BDB742913
CD195 Mouse anti-Human, Brilliant Violet 711, Clone: 3A9, BD Optibuild™
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB742913-Each-of-1 | In Stock | ₹ 47,614.14 |
BDB742913 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,614.14
GST (18%): ₹ 8,570.545
Total Price: ₹ 56,184.685
Antigen
CD195
Clone
3A9
Conjugate
Brilliant Violet 711
Gene Alias
CCR-5, Chemokine (C-C motif) receptor 5, CMKBR5, CKR5, CKR-5, CHEMR13
Immunogen
Human CCR5 Transfected Cell Line
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification
Monoclonal
Concentration
0.2mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG2a κ
Description
- The 3A9 monoclonal antibody recognizes CD195, which is also known as the chemokine receptor, CCR5, a seven transmembrane-spanning G protein-associated molecule
- The 3A9 antibody also reportedly cross-reacts with human CCR8
- Results of epitope mappingand sequence comparison between CCR5 and CCR8 reveals that the first three amino acid residues for these two receptors are identical: MDY (Met-Asp-Tyr)
- CCR5 belongs to the β-chemokine receptor family
- It is expressed on subsets of T lymphocytes, NK cells, monocytes, macrophages, and dendritic cells
- CCR5 regulates lymphocyte chemotaxis activation and transendothelial migration during inflammation
- It signals a response to at least three chemokines: RANTES and macrophage inflammatory protein-1 (MIP-1) α and β
- Additionally, CCR5 has beenfound to be a co-receptor for macrophage-tropic HIV-1 on CD4+ cells, a characteristic that is important in viral transmission
- Reports indicate that individuals who have partial (heterozygous) or complete (homozygous) deletion of the CCR5 allele, demonstrate resistance to HIV infection
- CCR5 has been clustered as CD195 in the VIIth HLDA workshop
- The antibody was conjugated to BD Horizon™ BV711 which is part of the BD Horizon Brilliant™ Violet family of dyes
- This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 711nm
- BD Horizon BV711 can be excited by the violet laser and detected in a filter used to detect Cy™5.5 / Alexa Fluor™ 700-like dyes (eg, 712/20nm filter)
- Due to the excitation and emission characteristics of the acceptor dye, there may be moderate spillover into the Alexa Fluor™ 700 and PerCP-Cy5.5 detectors
- However, the spillover can be corrected through compensation as with any other dye combination
- BV711 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 711 nm
- This dye offers a very bright choice for the violet laser
- Due to the excitation and emission characteristics of the acceptor dye, there may be moderate spillover into the Alexa Fluor™ 700 and PerCP-Cy5.5 detectors
- BV711 will also have moderate spillover into the BD Horizon Brilliant™ Violet 786 detector.
Compare Similar Items
Show Difference
Antigen: CD195
Clone: 3A9
Conjugate: Brilliant Violet 711
Gene Alias: CCR-5, Chemokine (C-C motif) receptor 5, CMKBR5, CKR5, CKR-5, CHEMR13
Immunogen: Human CCR5 Transfected Cell Line
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2a κ
Antigen:
CD195
Clone:
3A9
Conjugate:
Brilliant Violet 711
Gene Alias:
CCR-5, Chemokine (C-C motif) receptor 5, CMKBR5, CKR5, CKR-5, CHEMR13
Immunogen:
Human CCR5 Transfected Cell Line
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ
Antigen: CD195
Clone: 3A9
Conjugate: Brilliant Ultraviolet 395
Gene Alias: CCR-5, Chemokine (C-C motif) receptor 5, CMKBR5, CKR5, CKR-5, CHEMR13
Immunogen: Human CCR5 Transfected Cell Line
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2a κ
Antigen:
CD195
Clone:
3A9
Conjugate:
Brilliant Ultraviolet 395
Gene Alias:
CCR-5, Chemokine (C-C motif) receptor 5, CMKBR5, CKR5, CKR-5, CHEMR13
Immunogen:
Human CCR5 Transfected Cell Line
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ
Antigen: CD8b
Clone: 341
Conjugate: Brilliant Violet 421
Gene Alias: Cd8b, CD8beta, CD8 beta, CD8-beta, CD8β
Immunogen: CD8-positive Wistar rat splenic T-cell hybridomas
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG1 κ
Antigen:
CD8b
Clone:
341
Conjugate:
Brilliant Violet 421
Gene Alias:
Cd8b, CD8beta, CD8 beta, CD8-beta, CD8β
Immunogen:
CD8-positive Wistar rat splenic T-cell hybridomas
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG1 κ
Antigen: CD8b
Clone: 341
Conjugate: Brilliant Violet 605
Gene Alias: Cd8b, CD8beta, CD8 beta, CD8-beta, CD8β
Immunogen: CD8-positive Wistar rat splenic T-cell hybridomas
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG1 κ
Antigen:
CD8b
Clone:
341
Conjugate:
Brilliant Violet 605
Gene Alias:
Cd8b, CD8beta, CD8 beta, CD8-beta, CD8β
Immunogen:
CD8-positive Wistar rat splenic T-cell hybridomas
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG1 κ