BDB743008
CD275 Mouse anti-Human, Brilliant Violet 650, Clone: 2D3/B7-H2, BD Optibuild™
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB743008-Each-of-1 | In Stock | ₹ 47,400.24 |
BDB743008 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,400.24
GST (18%): ₹ 8,532.043
Total Price: ₹ 55,932.283
Antigen
CD275
Clone
2D3/B7-H2
Conjugate
Brilliant Violet 650
Gene Alias
ICOSLG, ICOS ligand, LICOS, B7-H2, B7 homolog 2, B7RP-1, GL50
Immunogen
Human B7-H2
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification
Monoclonal
Concentration
0.2mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG2b κ
Description
- The 2D3 monoclonal antibody specifically binds to CD275, which is also known as B7 homolog 2 (B7-H2/B7H2) and B7-related protein 1 (B7RP-1)
- CD275 is a type I transmembrane glycoprotein that belongs to the Ig superfamily
- CD275 is likewise known as Inducible T-cell co-stimulator ligand (ICOS Ligand /ICOSLG/ICOS-L)
- It can bind to CD278 (ICOS) and costimulate the proliferation and cytokine production of antigen-stimulated human T cells
- CD275 is variable expressed by subsets of B cells, monocytes, macrophages, dendritic cells and endothelial cells
- The antibody was conjugated to BD Horizon™ BV650 which is part of the BD Horizon Brilliant™ Violet family of dyes
- This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 650nm
- BD Horizon BV650 can be excited by the violet laser and detected in a filter used to detect APC-like dyes (eg, 660/20nm filter)
- Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors
- However, the spillover can be corrected through compensation as with any other dye combination
- BV650 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 650 nm
- Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors
- BV650 will have moderate spillover into the BD Horizon™ BV711 detector.
Compare Similar Items
Show Difference
Antigen: CD275
Clone: 2D3/B7-H2
Conjugate: Brilliant Violet 650
Gene Alias: ICOSLG, ICOS ligand, LICOS, B7-H2, B7 homolog 2, B7RP-1, GL50
Immunogen: Human B7-H2
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2b κ
Antigen:
CD275
Clone:
2D3/B7-H2
Conjugate:
Brilliant Violet 650
Gene Alias:
ICOSLG, ICOS ligand, LICOS, B7-H2, B7 homolog 2, B7RP-1, GL50
Immunogen:
Human B7-H2
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ
Antigen: CD275
Clone: 2D3/B7-H2
Conjugate: Brilliant Violet 786
Gene Alias: ICOSLG, ICOS ligand, LICOS, B7-H2, B7 homolog 2, B7RP-1, GL50
Immunogen: Human B7-H2
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2b κ
Antigen:
CD275
Clone:
2D3/B7-H2
Conjugate:
Brilliant Violet 786
Gene Alias:
ICOSLG, ICOS ligand, LICOS, B7-H2, B7 homolog 2, B7RP-1, GL50
Immunogen:
Human B7-H2
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ
Antigen: ROR1
Clone: 4A5
Conjugate: Brilliant Violet 605
Gene Alias: Neurotrophic tyrosine kinase, receptor-related 1, NTRKR1
Immunogen: Human ROR1 cDNA
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2b κ
Antigen:
ROR1
Clone:
4A5
Conjugate:
Brilliant Violet 605
Gene Alias:
Neurotrophic tyrosine kinase, receptor-related 1, NTRKR1
Immunogen:
Human ROR1 cDNA
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ
Antigen: ROR1
Clone: 4A5
Conjugate: Brilliant Violet 650
Gene Alias: Neurotrophic tyrosine kinase, receptor-related 1, NTRKR1
Immunogen: Human ROR1 cDNA
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2b κ
Antigen:
ROR1
Clone:
4A5
Conjugate:
Brilliant Violet 650
Gene Alias:
Neurotrophic tyrosine kinase, receptor-related 1, NTRKR1
Immunogen:
Human ROR1 cDNA
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ