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BDB743008

CD275 Mouse anti-Human, Brilliant Violet 650, Clone: 2D3/B7-H2, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB743008-Each-of-1 In Stock ₹ 49,306.00

BDB743008 - Each of 1

₹ 49,306.00

In Stock

Quantity

1

Base Price: ₹ 49,306.00

GST (18%): ₹ 8,875.08

Total Price: ₹ 58,181.08

Antigen

CD275

Clone

2D3/B7-H2

Conjugate

Brilliant Violet 650

Gene Alias

ICOSLG, ICOS ligand, LICOS, B7-H2, B7 homolog 2, B7RP-1, GL50

Immunogen

Human B7-H2

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG2b κ

Description

  • The 2D3 monoclonal antibody specifically binds to CD275, which is also known as B7 homolog 2 (B7-H2/B7H2) and B7-related protein 1 (B7RP-1)
  • CD275 is a type I transmembrane glycoprotein that belongs to the Ig superfamily
  • CD275 is likewise known as Inducible T-cell co-stimulator ligand (ICOS Ligand /ICOSLG/ICOS-L)
  • It can bind to CD278 (ICOS) and costimulate the proliferation and cytokine production of antigen-stimulated human T cells
  • CD275 is variable expressed by subsets of B cells, monocytes, macrophages, dendritic cells and endothelial cells
  • The antibody was conjugated to BD Horizon™ BV650 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 650nm
  • BD Horizon BV650 can be excited by the violet laser and detected in a filter used to detect APC-like dyes (eg, 660/20nm filter)
  • Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors
  • However, the spillover can be corrected through compensation as with any other dye combination
  • BV650 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 650 nm
  • Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors
  • BV650 will have moderate spillover into the BD Horizon™ BV711 detector.

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BD Biosciences

BDB743008

--

Antigen:
CD275
Clone:
2D3/B7-H2
Conjugate:
Brilliant Violet 650
Gene Alias:
ICOSLG, ICOS ligand, LICOS, B7-H2, B7 homolog 2, B7RP-1, GL50
Immunogen:
Human B7-H2
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ

Img

BD Biosciences

BDB743010

--

Antigen:
CD275
Clone:
2D3/B7-H2
Conjugate:
Brilliant Violet 786
Gene Alias:
ICOSLG, ICOS ligand, LICOS, B7-H2, B7 homolog 2, B7RP-1, GL50
Immunogen:
Human B7-H2
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ

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BD Biosciences

BDB743014

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Antigen:
ROR1
Clone:
4A5
Conjugate:
Brilliant Violet 605
Gene Alias:
Neurotrophic tyrosine kinase, receptor-related 1, NTRKR1
Immunogen:
Human ROR1 cDNA
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ

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BD Biosciences

BDB743015

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Antigen:
ROR1
Clone:
4A5
Conjugate:
Brilliant Violet 650
Gene Alias:
Neurotrophic tyrosine kinase, receptor-related 1, NTRKR1
Immunogen:
Human ROR1 cDNA
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ