Home Products Antibodies Primary Antibodies BDB743015
BDB743015

ROR1 Mouse anti-Human, Brilliant Violet 650, Clone: 4A5, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB743015-Each-of-1 In Stock ₹ 47,400.24

BDB743015 - Each of 1

₹ 47,400.24

In Stock

Quantity

1

Base Price: ₹ 47,400.24

GST (18%): ₹ 8,532.043

Total Price: ₹ 55,932.283

Antigen

ROR1

Clone

4A5

Conjugate

Brilliant Violet 650

Gene Alias

Neurotrophic tyrosine kinase, receptor-related 1, NTRKR1

Immunogen

Human ROR1 cDNA

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG2b κ

Description

  • The 4A5 monoclonal antibody binds to the glycosylated type I membrane protein ROR1 (Receptor-tyrosine-kinase-like Orphan Receptor 1)
  • The ROR1 and ROR2 related proteins are highly conserved evolutionarily and are primarily expressed during embryogenesis
  • ROR1 is not expressed on normal peripheral blood lymphocytes
  • ROR1 is similar to tropomyosin receptor kinase (Trk family) neurotropic receptors and shares a cysteine-rich domain with Frizzled receptors for Wnt-family signaling proteins, which are involved in the regulation of embryogenesis and carcinogenesis
  • Furthermore, there is mounting evidence that aberrant ROR1 expression contributes to human malignancy
  • The antibody was conjugated to BD Horizon™ BV650 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 650nm
  • BD Horizon BV650 can be excited by the violet laser and detected in a filter used to detect APC-like dyes (eg, 660/20nm filter)
  • Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors
  • However, the spillover can be corrected through compensation as with any other dye combination
  • BV650 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 650 nm
  • Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors
  • BV650 will have moderate spillover into the BD Horizon™ BV711 detector.

Compare Similar Items

Show Difference

Img

BD Biosciences

BDB743015

--

Antigen:
ROR1
Clone:
4A5
Conjugate:
Brilliant Violet 650
Gene Alias:
Neurotrophic tyrosine kinase, receptor-related 1, NTRKR1
Immunogen:
Human ROR1 cDNA
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ

Img

BD Biosciences

BDB743016

--

Antigen:
ROR1
Clone:
4A5
Conjugate:
Brilliant Violet 711
Gene Alias:
Neurotrophic tyrosine kinase, receptor-related 1, NTRKR1
Immunogen:
Human ROR1 cDNA
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ

Img

BD Biosciences

BDB743018

--

Antigen:
ROR1
Clone:
4A5
Conjugate:
Brilliant Ultraviolet 395
Gene Alias:
Neurotrophic tyrosine kinase, receptor-related 1, NTRKR1
Immunogen:
Human ROR1 cDNA
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ

Img

BD Biosciences

BDB743020

--

Antigen:
Vβ4 T-Cell Receptor
Clone:
KT4
Conjugate:
Brilliant Violet 510
Gene Alias:
TCR V beta 4, TCR Vβ4
Immunogen:
KT4 B10.D2 mouse T-cell clone I3
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2b κ