BDB743195
CD93 Mouse anti-Human, Brilliant Violet 421, Clone: R139, BD Optibuild™
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB743195-Each-of-1 | In Stock | ₹ 47,400.24 |
BDB743195 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,400.24
GST (18%): ₹ 8,532.043
Total Price: ₹ 55,932.283
Antigen
CD93
Clone
R139
Conjugate
Brilliant Violet 421
Gene Alias
C1QR1, C1qRP, C1qR(P), C1q/MBL/SPA Receptor, MXRA4, GR11, Dj737e23.1
Immunogen
Clq-CLF-binding proteins
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification
Monoclonal
Concentration
0.2mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG2b κ
Description
- The R139 monoclonal antibody specifically binds to CD93 which is also known as Complement component C1q receptor (C1qR), C1q receptor 1 (C1qR1), or Matrix-remodeling-associated protein 4 (MXRA4)
- The immunogen used to generate the R139 hybridoma was a preparation of CD93 protein
- Human CD93 is a transmembrane glycoprotein that is highly expressed on monocytes, macrophages, granulocytes, and endothelial cells but not on T and B lymphocytes
- CD93 is also known as the C1q/MBL/SPA Receptor as it binds C1q, the recognition subunit of the first component (C1) of the complement pathway, as well as MBL (Mannose-binding-lectin) and SPA (Pulmonary Surfactant Protein A)
- Human C1qRp is involved in the C1q-mediated enhancement of phagocytosis
- R139 is suitable to detect CD93 expression on cells of myeloid lineage by flow cytometry, and CD93 in cellular lysates by Western blotting or immunoprecipitation
- In addition, R139 reportedly neutralizes C1q-mediated enhancement of phagocytosis
- CD93 has also been reported to define a human stem cell population with hematopoietic and hepatic potential
- The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes
- With an Ex Max of 407nm and Em Max at 421nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50nm filter)
- BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates
- BV421 is a polymer-based dye excited by the violet laser and is one of the brightest fluorochromes offered by BD Biosciences
- Conjugates are typically 10 times brighter than Pacific Blue™ conjugates and are often as bright as or brighter than PE conjugates
- Due to nearly identical excitation and emission properties but different spillover characteristics, BD Horizon BV421, Pacific Blue™, and BD Horizon™ V450 cannot be used simultaneously.
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Antigen: CD93
Clone: R139
Conjugate: Brilliant Violet 421
Gene Alias: C1QR1, C1qRP, C1qR(P), C1q/MBL/SPA Receptor, MXRA4, GR11, Dj737e23.1
Immunogen: Clq-CLF-binding proteins
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2b κ
Antigen:
CD93
Clone:
R139
Conjugate:
Brilliant Violet 421
Gene Alias:
C1QR1, C1qRP, C1qR(P), C1q/MBL/SPA Receptor, MXRA4, GR11, Dj737e23.1
Immunogen:
Clq-CLF-binding proteins
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ
Antigen: CD93
Clone: R139
Conjugate: Brilliant Violet 510
Gene Alias: C1QR1, C1qRP, C1qR(P), C1q/MBL/SPA Receptor, MXRA4, GR11, Dj737e23.1
Immunogen: Clq-CLF-binding proteins
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2b κ
Antigen:
CD93
Clone:
R139
Conjugate:
Brilliant Violet 510
Gene Alias:
C1QR1, C1qRP, C1qR(P), C1q/MBL/SPA Receptor, MXRA4, GR11, Dj737e23.1
Immunogen:
Clq-CLF-binding proteins
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ
Antigen: CD93
Clone: R139
Conjugate: Brilliant Violet 605
Gene Alias: C1QR1, C1qRP, C1qR(P), C1q/MBL/SPA Receptor, MXRA4, GR11, Dj737e23.1
Immunogen: Clq-CLF-binding proteins
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2b κ
Antigen:
CD93
Clone:
R139
Conjugate:
Brilliant Violet 605
Gene Alias:
C1QR1, C1qRP, C1qR(P), C1q/MBL/SPA Receptor, MXRA4, GR11, Dj737e23.1
Immunogen:
Clq-CLF-binding proteins
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ
Antigen: CD93
Clone: R139
Conjugate: Brilliant Violet 650
Gene Alias: C1QR1, C1qRP, C1qR(P), C1q/MBL/SPA Receptor, MXRA4, GR11, Dj737e23.1
Immunogen: Clq-CLF-binding proteins
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2b κ
Antigen:
CD93
Clone:
R139
Conjugate:
Brilliant Violet 650
Gene Alias:
C1QR1, C1qRP, C1qR(P), C1q/MBL/SPA Receptor, MXRA4, GR11, Dj737e23.1
Immunogen:
Clq-CLF-binding proteins
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ