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BDB743356

CD196 (CCR6) Mouse anti-Human, BUV395, Clone: 11A9, BD Optibuild™

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB743356-Each-of-1 In Stock ₹ 47,614.14

BDB743356 - Each of 1

₹ 47,614.14

In Stock

Quantity

1

Base Price: ₹ 47,614.14

GST (18%): ₹ 8,570.545

Total Price: ₹ 56,184.685

Antigen

CD196 (CCR6)

Clone

11A9

Conjugate

Brilliant Ultraviolet 395

Gene Alias

BN-1, C-C chemokine receptor type 6, C-C CKR-6, CC-CKR-6, CCR-6, CD196

Immunogen

Human CD196/CCR6 Peptide

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

Description

  • The 11A9 monoclonal antibody specifically binds to CD196, which is also known as CCR6
  • CCR6 is a seven-transmembrane, G-protein-coupled, glycoprotein receptor that is a member of the beta chemokine receptor family
  • The human CCR6 /gene has been mapped to chromosome 6q27
  • CCR6 is a receptor for the CC chemokine CCL20/MIP-3alpha/LARC/Exodus and also binds with lower affinity to and mediates responses to beta-defensin2/hBD-2
  • CCR6 is predominantly expressed by B lymphocytes, certain subsets of effector and memory T cells and by immature dendritic cells but not by monocytes, NK cells, or granulocytyes
  • Skin-homing CLA (Cutaneous Lymphocyte Antigen)-positive memory T cells, Th1 cells, regulatory T cells and IL-17A-producing Th17 cells predominantly express high levels of CCR6
  • CCR6 mediates the trafficking of T, B, and dendritic cells to epithelial sites near the skin and mucosal surfaces during inflammatory and immunological responses
  • An N-terminal peptide of human CCR6 was used as an immunogen to generate the 11A9 hybridoma
  • The 11A9 antibody does not cross-react with human CCR1, CCR2, CCR3, CCR4, CCR5, CCR7, CCR8, CCR9, CXCR1, CXCR2, CXCR3, CXCR4 and CXCR5 receptors
  • This antibody is NOT a neutralizing antibody The antibody was conjugated to BD Horizon™ BUV395 which is part of the BD Horizon Brilliant™ Ultraviolet family of dyes
  • This dye has been exclusively developed by BD Biosciences to have minimal spillover into other detectors, making it an optimal choice for multicolor flow cytometry
  • With an Ex Max at 348 nm and an Em Max at 395 nm, BD Horizon BUV395 can be excited with a 355 nm laser and detected with a 379/28 filter
  • BUV395 is a UV-excitable dye that has been developed exclusively by BD Biosciences
  • With an excitation max of 348 nm and emission max of 395 nm, BUV395 can be excited by the 355nm laser and detected in a 379/28 filter
  • This dye is optimal for multicolor flow cytometry because it has little to no spillover into other detectors.

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BD Biosciences

BDB743356

--

Antigen:
CD196 (CCR6)
Clone:
11A9
Conjugate:
Brilliant Ultraviolet 395
Gene Alias:
BN-1, C-C chemokine receptor type 6, C-C CKR-6, CC-CKR-6, CCR-6, CD196
Immunogen:
Human CD196/CCR6 Peptide
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ

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BD Biosciences

BDB743360

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Antigen:
CD271
Clone:
C40-1457
Conjugate:
Brilliant Violet 711
Gene Alias:
NGFR, NGF Receptor, TNFRSF16
Immunogen:
Human NGFR Recombinant Protein
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ

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BD Biosciences

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Antigen:
CD271
Clone:
C40-1457
Conjugate:
Brilliant Violet 786
Gene Alias:
NGFR, NGF Receptor, TNFRSF16
Immunogen:
Human NGFR Recombinant Protein
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ

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BD Biosciences

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Antigen:
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Clone:
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Conjugate:
Brilliant Violet 421
Gene Alias:
Siglec-9, Siglec Y, FOAP-9, OBBP-LIKE
Immunogen:
__
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ