BDB743474

I-Ak Mouse anti-Mouse, Brilliant Violet 650, Clone: 10-3.6, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB743474-Each-of-1 In Stock ₹ 33,197.28

BDB743474 - Each of 1

₹ 33,197.28

In Stock

Quantity

1

Base Price: ₹ 33,197.28

GST (18%): ₹ 5,975.51

Total Price: ₹ 39,172.79

Antigen

I-Ak

Clone

10-3.6

Conjugate

Brilliant Violet 650

Gene Alias

Aβk

Immunogen

C3H mouse splenocytes

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG2a κ

Description

  • The 10-3.6 monoclonal antibody specifically recognizes theβchain of the I-A[k] MHC class II alloantigen
  • It cross-reacts with splenocytes from mice of the H-2[f], H-2[r], and H-2[s] haplotypes, from nonobese diabetic (NOD, H-2[g7]) mice, and with lymph node cells of BN, DA, WRA, and WRC rats
  • Reactivity with other haplotypes ( e.g., b, d, p, q /) has not been observed
  • Long-term in vivo /treatment with 10-3.6 mAb has been reported to prevent the spontaneous development of autoimmune insulin-dependent diabetes mellitus (IDDM) in female NOD mice
  • The antibody was conjugated to BD Horizon™ BV650 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 650nm
  • BD Horizon BV650 can be excited by the violet laser and detected in a filter used to detect APC-like dyes (eg, 660/20nm filter)
  • Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors
  • However, the spillover can be corrected through compensation as with any other dye combination
  • BV650 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 650 nm
  • Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors
  • BV650 will have moderate spillover into the BD Horizon™ BV711 detector.

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BD Biosciences

BDB743474

--


Antigen:
I-Ak

Clone:
10-3.6

Conjugate:
Brilliant Violet 650

Gene Alias:
Aβk

Immunogen:
C3H mouse splenocytes

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2a κ

Img

BD Biosciences

BDB743475

--


Antigen:
I-Ak

Clone:
10-3.6

Conjugate:
Brilliant Violet 711

Gene Alias:
Aβk

Immunogen:
C3H mouse splenocytes

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2a κ

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BD Biosciences

BDB743478

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Antigen:
CD162

Clone:
KPL-1

Conjugate:
Brilliant Violet 421

Gene Alias:
SELPLG, Selectin P ligand, P-selectin glycoprotein ligand 1, PSGL-1, CLA

Immunogen:
Human PSGL-1 Transfected Cell Line

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Img

BD Biosciences

BDB743479

--


Antigen:
CD162

Clone:
KPL-1

Conjugate:
Brilliant Violet 510

Gene Alias:
SELPLG, Selectin P ligand, P-selectin glycoprotein ligand 1, PSGL-1, CLA

Immunogen:
Human PSGL-1 Transfected Cell Line

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ