BDB743495
C3a Receptor Mouse anti-Human, Brilliant Violet 650, Clone: hC3aRZ8, BD Optibuild™
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB743495-Each-of-1 | In Stock | ₹ 47,400.24 |
BDB743495 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,400.24
GST (18%): ₹ 8,532.043
Total Price: ₹ 55,932.283
Antigen
C3a Receptor
Clone
hC3aRZ8
Conjugate
Brilliant Violet 650
Gene Alias
C3AR, C3a-R, C3AR1, C3a anaphylatoxin chemotactic receptor, AZ3B
Immunogen
Human C3aR
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification
Monoclonal
Concentration
0.2mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG2b
Description
- The hC3aRZ8 monoclonal antibody specifically binds to the human C3a Receptor (C3aR)
- C3aR is a seven-transmembrane glycoprotein, G-protein-coupled receptor that is the specific receptor for C3a anaphylatoxin
- The C3aR consists of 482 amino acids forming a single polypeptide chain that is encoded by the C3AR1 /gene located on chromosome 12 (location 12p13.31)
- C3aR are expressed by eosinophils, basophils, neutrophils, dendritic cells, monocytes, macrophages, endothelial cells and some T cells
- C3a is a bioactive cleavage product released from Complement Component 3 (C3) during complement activation
- C3a plays a role in a variety of cellular immune responses as well as being a potent pro-inflammatory agent
- In response to bound C3a, this receptor stimulates cellular responses including chemotaxis, granule enzyme release and superoxide anion production and causes increased vascular permeability
- In vivo, C3a production can initiate, contribute to, or exacerbate the inflammatory reactions seen in gram-negative bacterial sepsis, trauma, ARDS, ischemic heart disease, post-dialysis syndrome, and several autoimmune diseases including rheumatoid arthritis, lupus erythematosus, and acute glomerulonephritis
- The antibody was conjugated to BD Horizon™ BV650 which is part of the BD Horizon Brilliant™ Violet family of dyes
- This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 650nm
- BD Horizon BV650 can be excited by the violet laser and detected in a filter used to detect APC-like dyes (eg, 660/20nm filter)
- Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors
- However, the spillover can be corrected through compensation as with any other dye combination
- BV650 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 650 nm
- Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors
- BV650 will have moderate spillover into the BD Horizon™ BV711 detector.
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Show Difference
Antigen: C3a Receptor
Clone: hC3aRZ8
Conjugate: Brilliant Violet 650
Gene Alias: C3AR, C3a-R, C3AR1, C3a anaphylatoxin chemotactic receptor, AZ3B
Immunogen: Human C3aR
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2b
Antigen:
C3a Receptor
Clone:
hC3aRZ8
Conjugate:
Brilliant Violet 650
Gene Alias:
C3AR, C3a-R, C3AR1, C3a anaphylatoxin chemotactic receptor, AZ3B
Immunogen:
Human C3aR
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b
Antigen: C3a Receptor
Clone: hC3aRZ8
Conjugate: Brilliant Violet 711
Gene Alias: C3AR, C3a-R, C3AR1, C3a anaphylatoxin chemotactic receptor, AZ3B
Immunogen: Human C3aR
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2b
Antigen:
C3a Receptor
Clone:
hC3aRZ8
Conjugate:
Brilliant Violet 711
Gene Alias:
C3AR, C3a-R, C3AR1, C3a anaphylatoxin chemotactic receptor, AZ3B
Immunogen:
Human C3aR
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b
Antigen: CD138
Clone: MI15
Conjugate: Brilliant Violet 650
Gene Alias: Syndecan, SDC, Syndecan 1, SDC1, SYND1
Immunogen: Human U266 and XG-1 Myeloma Cell Lines
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD138
Clone:
MI15
Conjugate:
Brilliant Violet 650
Gene Alias:
Syndecan, SDC, Syndecan 1, SDC1, SYND1
Immunogen:
Human U266 and XG-1 Myeloma Cell Lines
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD161f
Clone: C8
Conjugate: Brilliant Violet 650
Gene Alias: __
Immunogen: __
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Refrigerate (2 to 8°C)
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: __
Host Species: Rat
Purification Method: __
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG1 κ
Antigen:
CD161f
Clone:
C8
Conjugate:
Brilliant Violet 650
Gene Alias:
__
Immunogen:
__
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Refrigerate (2 to 8°C)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
__
Host Species:
Rat
Purification Method:
__
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG1 κ