BDB743500

CD138 Mouse anti-Human, Brilliant Violet 650, Clone: MI15, BD Optibuild™

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB743500-Each-of-1 In Stock ₹ 47,400.24

BDB743500 - Each of 1

₹ 47,400.24

In Stock

Quantity

1

Base Price: ₹ 47,400.24

GST (18%): ₹ 8,532.043

Total Price: ₹ 55,932.283

Antigen

CD138

Clone

MI15

Conjugate

Brilliant Violet 650

Gene Alias

Syndecan, SDC, Syndecan 1, SDC1, SYND1

Immunogen

Human U266 and XG-1 Myeloma Cell Lines

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

Description

  • The MI15 monoclonal antibody specifically binds to CD138 (Syndecan-1), an 85-92 kDa single chain transmembrane protein, which is strongly expressed on multiple-myeloma-derived cell lines and malignant plasma cell populations
  • It is also expressed on pre-B cells, immature B cells, and plasma cells, but not on mature circulating B-lymphocytes
  • Syndecan-1 is a member of the transmembrane heparan sulfate proteoglycans family
  • It is also expressed on some non-hematopoietic cells, including embryonic mesenchymal cells, vascular smooth muscle cells, endothelial and neural cells
  • CD138 binds to many extracellular matrix proteins through its heparan sulfate side-chains, like fibronectin, collagen types I, III, and V, tenascin, thrombospondin, and antithrombin III
  • It is considered an extracellular matrix receptor that may serve as a co-receptor for fibroblast growth factor and related molecules
  • Monoclonal antibody MI15 blocks the binding of clone B-B4 but not clone DL-101 (other anti-syndecan-1 antibodies) by flow cytometric analysis
  • The antibody was conjugated to BD Horizon™ BV650 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 650nm
  • BD Horizon BV650 can be excited by the violet laser and detected in a filter used to detect APC-like dyes (eg, 660/20nm filter)
  • Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors
  • However, the spillover can be corrected through compensation as with any other dye combination
  • BV650 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 650 nm
  • Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors
  • BV650 will have moderate spillover into the BD Horizon™ BV711 detector.

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BD Biosciences

BDB743500

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Antigen:
CD138

Clone:
MI15

Conjugate:
Brilliant Violet 650

Gene Alias:
Syndecan, SDC, Syndecan 1, SDC1, SYND1

Immunogen:
Human U266 and XG-1 Myeloma Cell Lines

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Img

BD Biosciences

BDB743514

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Antigen:
CD161f

Clone:
C8

Conjugate:
Brilliant Violet 650

Gene Alias:
__

Immunogen:
__

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Refrigerate (2 to 8°C)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
__

Host Species:
Rat

Purification Method:
__

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG1 κ

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BD Biosciences

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Antigen:
CD161f

Clone:
C8

Conjugate:
Brilliant Violet 711

Gene Alias:
__

Immunogen:
__

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Refrigerate (2 to 8°C)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
__

Host Species:
Rat

Purification Method:
__

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG1 κ

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Antigen:
CD114

Clone:
LMM741

Conjugate:
Brilliant Violet 510

Gene Alias:
GCSFR, G-CSF Receptor, G-CSF-R, G-CSFR, HG-CSFR, CSF3R

Immunogen:
G-CSFR cDNA transfected cells.

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ