BDB743710

CD335 (NKp46) Mouse anti-Human, Brilliant Violet 605, Clone: 9E2/NKp46 (also known as 9-E2), BD Optibuild™

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB743710-Each-of-1 In Stock ₹ 47,614.14

BDB743710 - Each of 1

₹ 47,614.14

In Stock

Quantity

1

Base Price: ₹ 47,614.14

GST (18%): ₹ 8,570.545

Total Price: ₹ 56,184.685

Antigen

CD335 (NKp46)

Clone

9E2/NKp46 (also known as 9-E2)

Conjugate

Brilliant Violet 605

Gene Alias

NCR1, NK-p46, hNKp46, LY94, Natural cytotoxicity triggering receptor 1

Immunogen

Human NKp46 Recombinant Protein

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

Description

  • The 9E2/Nkp46 monoclonal antibody specifically binds to CD335
  • CD335 is also known as the Natural killer cell p46-related protein (NKp46) and the Natural cytotoxicity triggering receptor 1 (NCR1)
  • CD335 is a 46 kDa type I membrane glycoprotein that is expressed on resting and activated NK cells
  • Its extracellular region contains two C2-type, Ig-like domains
  • The transmembrane domain contains a positively charged amino acid (Arg) which could be involved in stabilizing the association with CD3ζ
  • Its intracellular region does not contain immunoreceptor tyrosine-based activating motifs (ITAM), but it is linked to intracytoplasmic transduction machinery by its association with CD3ζ and FcεRIγ adaptor proteins.CD335 along with NKp30 and NKp44 are referred to as natural cytotoxicity receptors (NCR)
  • These receptors play very important roles in cells that kill virus-infected target cells, tumor cells and MHC-class I-unprotected cells
  • This antibody is conjugated to BD Horizon™ BV605 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • With an Ex Max of 407nm and Em Max of 602nm, BD Horizon BV605 can be excited by a violet laser and detected with a standard 610/20nm filter set
  • BD Horizon BV605 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an Em max at 605nm
  • Due to the excitation of the acceptor dye by the green (532 nm) and yellow-green (561 nm) lasers, there will be significant spillover into the PE and BD Horizon PE-CF594 detectors off the green or yellow-green lasers
  • BD Horizon BV605 conjugates are very bright, often exhibiting brightness equivalent to PE conjugates and can be used as a third color off of the violet laser
  • BV605 is a tandem fluorochrome that combines BD Horizon BV421 and Cy™3.5
  • These conjugates are very bright, exhibiting similar brightness to equivalent PE conjugates
  • Due to the excitation of Cy3.5 by the green (532nm) and yellow-green (561nm) lasers, there will be significant spillover of the BD Horizon BV605 signal into the PE and BD Horizon PE-CF594 detectors off the green or yellow-green lasers.

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BD Biosciences

BDB743710

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Antigen:
CD335 (NKp46)

Clone:
9E2/NKp46 (also known as 9-E2)

Conjugate:
Brilliant Violet 605

Gene Alias:
NCR1, NK-p46, hNKp46, LY94, Natural cytotoxicity triggering receptor 1

Immunogen:
Human NKp46 Recombinant Protein

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Img

BD Biosciences

BDB743712

--


Antigen:
CD324 (E-Cadherin)

Clone:
67A4

Conjugate:
Brilliant Violet 421

Gene Alias:
E-cadherin, CD324, CDH1, CADH1, Cadherin-1, ECAD, CDHE, Arc-1, LCAM, UVO

Immunogen:
Human Breast Tumor Cell Line

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Img

BD Biosciences

BDB743713

--


Antigen:
CD324 (E-Cadherin)

Clone:
67A4

Conjugate:
Brilliant Violet 605

Gene Alias:
E-cadherin, CD324, CDH1, CADH1, Cadherin-1, ECAD, CDHE, Arc-1, LCAM, UVO

Immunogen:
Human Breast Tumor Cell Line

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Img

BD Biosciences

BDB743714

--


Antigen:
CD324 (E-Cadherin)

Clone:
67A4

Conjugate:
Brilliant Violet 650

Gene Alias:
E-cadherin, CD324, CDH1, CADH1, Cadherin-1, ECAD, CDHE, Arc-1, LCAM, UVO

Immunogen:
Human Breast Tumor Cell Line

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ